[HTML][HTML] Neonatal oxytocin gives the tempo of social and feeding behaviors

F Muscatelli, V Matarazzo, B Chini - Frontiers in Molecular …, 2022 - frontiersin.org
The nonapeptide oxytocin (OT) is a master regulator of the social brain in early infancy,
adolescence, and adult life. Here, we review the postnatal dynamic development of OT …

[HTML][HTML] Modulation of the thermosensory system by oxytocin

U Zayan, L Caccialupi Da Prato, F Muscatelli… - Frontiers in Molecular …, 2023 - frontiersin.org
Oxytocin (OT) is a neurohormone involved early in neurodevelopment and is implicated in
multiple functions, including sensory modulation. Evidence of such modulation has been …

Differential DNA methylation in iPSC-derived dopaminergic neurons: a step forward on the role of SNORD116 microdeletion in the pathophysiology of addictive …

J Salles, S Eddiry, S Amri, M Galindo… - Molecular …, 2024 - nature.com
Introduction A microdeletion including the SNORD116 gene (SNORD116 MD) has been
shown to drive the Prader-Willi syndrome (PWS) features. PWS is a neurodevelopmental …

Heralding a new era of oxytocinergic research: New tools, new problems?

F Althammer - Journal of Neuroendocrinology, 2023 - Wiley Online Library
According to classic neuroendocrinology, hypothalamic oxytocin cells can be categorized
into parvo‐and magnocellular neurons. However, research in the last decade provided …

Analysis of the hypothalamic oxytocin system and oxytocin receptor‐expressing astrocytes in a mouse model of Prader–Willi syndrome

F Althammer, MC Wimmer, Q Krabichler… - Journal of …, 2022 - Wiley Online Library
Prader–Willi syndrome (PWS) is a neurodevelopmental disorder characterized by
hyperphagia, obesity, developmental delay and intellectual disability. Studies suggest …

The efficacy of intranasal oxytocin in patients with Prader-Willi syndrome: A systematic review and meta-analysis

NM Shalma, MA Alsharabasy, AM Taha… - Diabetes & Metabolic …, 2023 - Elsevier
Abstract Background and aims Prader-Willi Syndrome (PWS) is a rare genetic disease.
Oxytocin is a neuropeptide hormone that impacts fear, and social recognition. Intranasal …

[HTML][HTML] Oxytocin: A multi-functional biomolecule with potential actions in dysfunctional conditions; from animal studies and beyond

AS Tsingotjidou - Biomolecules, 2022 - mdpi.com
Oxytocin is a hormone secreted from definite neuroendocrine neurons located in specific
nuclei in the hypothalamus (mainly from paraventricular and supraoptic nuclei), and its main …

New avenues for pharmacological management of hyperphagia and associated behavioral disorders in Prader-Willi syndrome

JM Castellano, AB Ariza-Jimenez… - The Journal of …, 2023 - academic.oup.com
Prader-Willi syndrome (PWS) is a rare neurodevelopmental disorder, commonly linked to
hyperphagia and related behavioral and metabolic disturbances, such as food obsession …

[HTML][HTML] The Pivotal Role of Oxytocin's Mechanism of Thermoregulation in Prader-Willi Syndrome, Schaaf-Yang Syndrome, and Autism Spectrum Disorder

C Camerino - International Journal of Molecular Sciences, 2024 - mdpi.com
Oxytocin (Oxt) regulates thermogenesis, and altered thermoregulation results in Prader-Willi
syndrome (PWS), Schaaf-Yang syndrome (SYS), and Autism spectrum disorder (ASD). PWS …

Acquiring social safety engages oxytocin neurons in the supraoptic nucleus–role of Magel2 deficiency

P Chakraborty, H Lamat, EM Andre, P Fontanaud… - …, 2024 - karger.com
Methods Using Magel2 knockout mice, an animal model of Prader Willi Syndrome (PWS)
and Schaaf-Yang Syndrome (SYS), we tested memory of social fear and safety after a …