[HTML][HTML] The role of interleukin-8 in lung inflammation and injury: implications for the management of COVID-19 and hyperinflammatory acute respiratory distress …

MC Cesta, M Zippoli, C Marsiglia, EM Gavioli… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus—2 (SARS CoV-2) has resulted in the
global spread of Coronavirus Disease 2019 (COVID-19) and an increase in complications …

[HTML][HTML] Acute lung injury–from pathophysiology to treatment

D Mokra - Physiological research, 2020 - ncbi.nlm.nih.gov
Acute lung injury is characterized by acute respiratory insufficiency with tachypnea, cyanosis
refractory to oxygen, decreased lung compliance, and diffuse alveolar infiltrates on chest X …

[HTML][HTML] Pulmonary fibrosis as a result of acute lung inflammation: molecular mechanisms, relevant in vivo models, prognostic and therapeutic approaches

IA Savin, MA Zenkova, AV Sen'kova - International journal of molecular …, 2022 - mdpi.com
Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …

[HTML][HTML] Role of interleukin-6 in vascular health and disease

P Villar-Fincheira, F Sanhueza-Olivares… - Frontiers in molecular …, 2021 - frontiersin.org
IL-6 is usually described as a pleiotropic cytokine produced in response to tissue injury or
infection. As a pro-inflammatory cytokine, IL-6 activates innate and adaptative immune …

[HTML][HTML] Markers of endothelial and epithelial pulmonary injury in mechanically ventilated COVID-19 ICU patients

S Spadaro, A Fogagnolo, G Campo, O Zucchetti… - Critical care, 2021 - Springer
Background Biomarkers can be used to detect the presence of endothelial and/or alveolar
epithelial injuries in case of ARDS. Angiopoietin-2 (Ang-2), soluble intercellular adhesion …

Coronavirus disease 2019–associated coagulopathy

G Lippi, F Sanchis-Gomar, EJ Favaloro, CJ Lavie… - Mayo Clinic …, 2021 - Elsevier
Patients with the severe form of coronavirus disease 2019 (COVID-19) have been frequently
found to suffer from both arterial and venous thrombotic events due to the perpetuation of a …

[HTML][HTML] Factors influencing liberation from mechanical ventilation in coronavirus disease 2019: multicenter observational study in fifteen Italian ICUs

L Gamberini, T Tonetti, S Spadaro, G Zani… - Journal of intensive …, 2020 - Springer
Background A large proportion of patients with coronavirus disease 2019 (COVID-19)
develop severe respiratory failure requiring admission to the intensive care unit (ICU) and …

Immunobiology and immunotherapy of COVID‐19: A clinically updated overview

A Esmaeilzadeh, R Elahi - Journal of cellular physiology, 2021 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a new member of the
coronavirus family that can cause coronavirus disease 2019 (COVID‐19). COVID‐9 has …

[HTML][HTML] Diagnosis and treatment of acute pulmonary inflammation in critically ill patients: the role of inflammatory biomarkers

S Chalmers, A Khawaja, PM Wieruszewski… - World journal of …, 2019 - ncbi.nlm.nih.gov
Pneumonia and acute respiratory distress syndrome are common and important causes of
respiratory failure in the intensive care unit with a significant impact on morbidity, mortality …

Frailty in critical care medicine: a review

JC De Biasio, AM Mittel, AL Mueller… - Anesthesia & …, 2020 - journals.lww.com
Traditional approaches to clinical risk assessment utilize age as a marker of increased
vulnerability to stress. Relatively recent advancements in the study of aging have led to the …