SARS-CoV-2: Targeted managements and vaccine development

M Bakhiet, S Taurin - Cytokine & growth factor reviews, 2021 - Elsevier
Infection with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) results in
diverse outcomes. The symptoms appear to be more severe in males older than 65 and …

[HTML][HTML] Intravenous immunoglobulins at the crossroad of autoimmunity and viral infections

C Perricone, P Triggianese, R Bursi, G Cafaro… - Microorganisms, 2021 - mdpi.com
Intravenous immunoglobulins (IVIG) are blood preparations pooled from the plasma of
donors that have been first employed as replacement therapy in immunodeficiency. IVIG …

[HTML][HTML] Convalescent plasma for the prevention and treatment of COVID-19: a systematic review and quantitative analysis

HT Peng, SG Rhind, A Beckett - JMIR Public Health and …, 2021 - publichealth.jmir.org
Background: The COVID-19 pandemic, caused by a novel coronavirus termed SARS-CoV-2,
has spread quickly worldwide. Convalescent plasma (CP) obtained from patients following …

[HTML][HTML] Efficacy and outcome of remdesivir and tocilizumab combination against dexamethasone for the treatment of severe COVID-19: A randomized controlled trial

ATM Mohiuddin Chowdhury, A Kamal… - Frontiers in …, 2022 - frontiersin.org
Objective: In this study, we investigated the efficacy and safety of remdesivir and tocilizumab
combination therapy against dexamethasone for the management of severe COVID-19 …

Convalescent plasma therapy for management of COVID-19: Perspectives and deployment in the current global pandemic

N Samad, TE Sodunke, HA Banna… - … and healthcare policy, 2020 - Taylor & Francis
The world is striving against the severe crisis of the COVID-19 pandemic. Healthcare
professionals are struggling to treat their patients based on nonspecific therapies. Amidst …

[HTML][HTML] Immunomodulatory therapy for the management of critically ill patients with COVID-19: A narrative review

D Andaluz-Ojeda, P Vidal-Cortes, ÁA Sanz… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the
causative agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic …

[HTML][HTML] Convalescent plasma therapy-a silver lining for COVID-19 management?

S Saha, S Kadam - Hematology, transfusion and cell therapy, 2021 - SciELO Brasil
The COVID-19 pandemic has pushed the world towards social, economic, and medical
challenges. Scientific research in medicine is the only means to overcome novel and …

Prognosis and the Global Impact of the COVID-19 Pandemic-A Comprehensive Review

S Zainab, SMF Hassan, R Noor, F Khalid… - RADS Journal of …, 2021 - jpps.juw.edu.pk
Background: The novel coronavirus 2019 or SARS-CoV-2 appeared first in the December,
2019, in the Wuhan, China. The virus later effected almost every part of the world. Aim of the …

[HTML][HTML] Convalescent plasma therapy in aHUS patient with SARS-CoV-2 infection

ED Stea, V Pronzo, F Pesce… - Journal of Clinical …, 2022 - clinnephrologyjournal.com
Endotheliosis, thrombotic microangiopathy and complement system over activation have
been described as pathologic features of tissue damage in the setting of coronavirus …

Development of a minicircular DNA vaccine against COVID-19

CL Ventura - 2022 - ubibliorum.ubi.pt
Nucleic acid vaccines have proven to be a promising technology in the fight against global
threats such as coronavirus disease (COVID-19). Minicircle DNA (mcDNA) is an innovative …