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The pathobiology of alopecia areata (AA), one of the most frequent autoimmune diseases
and a major unsolved clinical problem, has intrigued dermatologists, hair biologists and …

The etiology of alopecia areata (AA), a putative autoimmune disease characterized by
sudden hair loss, has remained obscure. It is not understood, how the characteristic …

Alopecia areata is a tissue-restricted autoimmune disease of the hair follicle, which results in
hair loss and baldness. It is often psychologically devastating. The role of T lymphocytes in …

Alopecia areata (AA) is a CD8+ T-cell dependent autoimmune disease of the hair follicle
(HF) in which the collapse of HF immune privilege (IP) plays a key role. Mast cells (MCs) are …

Background: Oral corticosteroids may be effective in the treatment of severe alopecia areata
(AA), but the side effects of prolonged therapy limit their use. The benefit of a single …

One of the most potent pro-inflammatory mediators is the earlyacting cytokine interleukin-1.
Its actions are regulated by a structurally related anti-inflammatory cytokine known as the …

Cytokines play a role in alopecia areata. We used immunohistochemical and in situ
hybridization studies to demonstrate the persistence of pro-inflammatory as well as apoptotic …

Alopecia areata is a common and sometimes disabling chronic inflammatory disorder of the
hair and nails. Genetic factors, that are now beginning to be identified, are undoubtedly …

Considerable indirect evidence suggests that T lymphocytes have a role in the pathogenesis
of psoriasis. The goal of this study was to directly test the ability of T cells to maintain …