Challenges and considerations during in vitro production of porcine embryos

PR Chen, BK Redel, KC Kerns, LD Spate, RS Prather - Cells, 2021 - mdpi.com
Genetically modified pigs have become valuable tools for generating advances in animal
agriculture and human medicine. Importantly, in vitro production and manipulation of …

RNA m6A modifications in mammalian gametogenesis and pregnancy

X Sui, A Klungland, L Gao - Reproduction, 2023 - rep.bioscientifica.com
In brief RNA modifications play key roles in regulating various biological processes. This
article discusses and summarizes the recent advances of RNA m6A modifications related to …

EpiFactors 2022: expansion and enhancement of a curated database of human epigenetic factors and complexes

D Marakulina, IE Vorontsov, IV Kulakovskiy… - Nucleic Acids …, 2023 - academic.oup.com
We present an update of EpiFactors, a manually curated database providing information
about epigenetic regulators, their complexes, targets, and products which is openly …

Parental exposure to environmentally relevant concentrations of bisphenol-A bis (diphenyl phosphate) impairs vascular development in offspring through DNA/RNA …

C Wang, J Xu, S Luo, J Huang, D Ji, X Qiu… - Environmental …, 2023 - ACS Publications
Bisphenol-A bis (diphenyl phosphate)(BDP) has been increasingly detected in indoor
environmental and human samples. Little is known about its developmental toxicity …

[HTML][HTML] Genetic regulation of N6-methyladenosine-RNA in mammalian gametogenesis and embryonic development

Y Chang, M Yi, J Wang, Z Cao, T Zhou, W Ge… - Frontiers in cell and …, 2022 - frontiersin.org
Emerging evidence shows that m6A is the most abundant modification in eukaryotic RNA
molecules. It has only recently been found that this epigenetic modification plays an …

Effects of exogenous glycine betaine and cycloleucine on photosynthetic capacity, amino acid composition, and hormone metabolism in Solanum melongena L.

T Niu, J Zhang, J Li, X Gao, H Ma, Y Gao, Y Chang… - Scientific Reports, 2023 - nature.com
Although exogenous glycine betaine (GB) and cycloleucine (Cyc) have been reported to
affect animal cell metabolism, their effects on plant growth and development have not been …

Comparative evaluation of production performances of cloned pigs derived from superior Duroc boars

J Shi, L Xiao, B Tan, L Luo, Z Li, L Hong, J Yang… - Animal Reproduction …, 2022 - Elsevier
Since pig was successfully cloned in 2000, somatic cell nuclear transfer (SCNT) became a
promising technique in preserving and expanding the genetics of superior boars. Assessing …

In Search of a Function for the N6-Methyladenosine in Epitranscriptome, Autophagy and Neurodegenerative Diseases

N Suga, Y Ikeda, S Yoshikawa, K Taniguchi… - Neurology …, 2023 - mdpi.com
Changes in epitranscriptome with N6-methyladenine (m6A) modification could be involved
in the development of multiple diseases, which might be a prevalent modification of …

mRNA m6A 甲基化修饰对干细胞生物学特性的影响

韩韦钰, 赵永超, 赵然尊 - 中国组织工程研究, 2023 - cjter.com
mRNA m6A甲基化修饰对干细胞生物学特性的影响 中国组织工程研究 首页 关于本刊 编委会
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[HTML][HTML] Regulatory role of m6A epitranscriptomic modifications in normal development and congenital malformations during embryogenesis

Y Yao, P Liu, Y Li, W Wang, H Jia, Y Bai, Z Yuan… - Biomedicine & …, 2024 - Elsevier
The discovery of N6-methyladenosine (m 6 A) methylation and its role in translation has led
to the emergence of a new field of research. Despite accumulating evidence suggesting that …