Carbon nanotube-mediated platinum-based drug delivery for the treatment of cancer: Advancements and future perspectives

MS Khan, BHJ Gowda, N Hasan, G Gupta… - European Polymer …, 2024 - Elsevier
Platinum-based drugs are among the few potent chemotherapeutic agents used in cancer
treatment. The discovery of cisplatin played a pivotal role, leading to the subsequent …

Macromolecules incorporating transition metals in the treatment and detection of cancer and infectious diseases: Progress over the last decade

A Abd-El-Aziz, SA Ahmed, X Zhang, N Ma… - Coordination Chemistry …, 2024 - Elsevier
The past decade has seen tremendous demand for the production of new materials based
on metal-containing macromolecules. Many research groups have dedicated their time and …

[HTML][HTML] From the Discovery of Targets to Delivery Systems: How to Decipher and Improve the Metallodrugs' Actions at a Molecular Level

I Iacobucci, S La Manna, I Cipollone, V Monaco… - Pharmaceutics, 2023 - mdpi.com
Metals are indispensable for the life of all organisms, and their dysregulation leads to
various disorders due to the disruption of their homeostasis. Nowadays, various transition …

Dinuclear Rhenium (I) Tricarbonyl Complexes as Anticancer Drug Candidates

N Montesdeoca, RL Borkar… - … A European Journal, 2024 - Wiley Online Library
Cancer is one of the deadliest diseases worldwide. Chemotherapy remains one of the most
dominant forms for anticancer treatment. Despite their clinical success, the used …

Series of Desloratadine Platinum (IV) Hybrids Displaying Potent Antimetastatic Competence by Inhibiting Epithelial–Mesenchymal Transition and Arousing Immune …

M Zhang, Y Chen, Z Liu, M Liu… - Journal of Medicinal …, 2024 - ACS Publications
Metastasis is the major obstacle to the survival of cancer patients. Herein, a series of new
desloratadine platinum (IV) conjugates with promising antiproliferative and antimetastatic …

Tailoring drug delivery systems by microfluidics for tumor therapy

Q Zhang, G Kuang, L Wang, L Fan, Y Zhao - Materials Today, 2024 - Elsevier
Drug delivery systems (DDSs) for tumor treatment is a specialized method aimed at
transporting therapeutic substances, especially anticancer drugs, to specific target areas in …

Visible and Red Light-Triggered Anticancer Profile of a Ferrocene-Re (I)-Tricarbonyl Conjugate: Experimental and Theoretical Studies

R Kushwaha, A Upadhyay, S Peters, AK Yadav… - Langmuir, 2024 - ACS Publications
We have red-shifted the light absorbance property of a Re (I)-tricarbonyl complex via distant
conjugation of a ferrocene moiety and developed a novel complex ReFctp,[Re (Fctp)(CO) …

Cu (ii) flavonoids as potential photochemotherapeutic agents

N Das, B Bora, A Upadhyay, D Das, A Bera… - Dalton …, 2024 - pubs.rsc.org
Flavonoids, naturally derived polyphenolic compounds, have received significant attention
due to their remarkable biochemical properties that offer substantial health benefits to …

[HTML][HTML] Copper (II) Complexes with 1-(Isoquinolin-3-yl) heteroalkyl-2-ones: Synthesis, Structure and Evaluation of Anticancer, Antimicrobial and Antioxidant Potential

Ł Balewski, T Plech, I Korona-Głowniak… - International Journal of …, 2023 - mdpi.com
Four copper (II) complexes, C1–4, derived from 1-(isoquinolin-3-yl) heteroalkyl-2-one
ligands L1–4 were synthesized and characterized using an elemental analysis, IR …

Development of Platinum Complexes for Tumor Chemoimmunotherapy

S Jin, Y Guo, X Wang - Chemistry–A European Journal, 2024 - Wiley Online Library
Platinum complexes are potential antitumor drugs in chemotherapy. Their impact on tumor
treatment could be greatly strengthened by combining with immunotherapy. Increasing …