[HTML][HTML] Advances in antibody phage display technology

L Ledsgaard, A Ljungars, C Rimbault, CV Sørensen… - Drug Discovery …, 2022 - Elsevier
Phage display technology can be used for the discovery of antibodies for research,
diagnostic, and therapeutic purposes. In this review, we present and discuss key parameters …

Pichia pastoris: A highly successful expression system for optimal synthesis of heterologous proteins

M Karbalaei, SA Rezaee… - Journal of cellular …, 2020 - Wiley Online Library
One of the most important branches of genetic engineering is the expression of recombinant
proteins using biological expression systems. Nowadays, different expression systems are …

Industrial Production of Proteins with Pichia pastorisKomagataella phaffii

GD Barone, A Emmerstorfer-Augustin, A Biundo… - Biomolecules, 2023 - mdpi.com
Since the mid-1960s, methylotrophic yeast Komagataella phaffii (previously described as
Pichia pastoris) has received increasing scientific attention. The interest for the industrial …

Factors involved in heterologous expression of proteins in E. coli host

M Pouresmaeil, S Azizi-Dargahlou - Archives of Microbiology, 2023 - Springer
The production of recombinant proteins is one of the most significant achievements of
biotechnology in the last century. These proteins are produced in the eukaryotic or …

[PDF][PDF] An overview of heterologous expression host systems for the production of recombinant proteins

AR Gomes, SM Byregowda, BM Veeregowda… - Adv. Anim. Vet …, 2016 - academia.edu
With the advent of recombinant DNA technology, cloning and expression of numerous
mammalian genes in different systems have been explored to produce many therapeutics …

Designing electrospun fiber platforms for efficient delivery of genetic material and genome editing tools

DL Puhl, D Mohanraj, DW Nelson, RJ Gilbert - Advanced drug delivery …, 2022 - Elsevier
Electrospun fibers are versatile biomaterial platforms with great potential to support
regeneration. Electrospun fiber characteristics such as fiber diameter, degree of alignment …

The recombinant expression systems for structure determination of eukaryotic membrane proteins

Y He, K Wang, N Yan - Protein & cell, 2014 - academic.oup.com
Eukaryotic membrane proteins, many of which are key players in various biological
processes, constitute more than half of the drug targets and represent important candidates …

[HTML][HTML] Ferulic acid, a natural polyphenol, protects against osteoporosis by activating SIRT1 and NF-κB in neonatal rats with glucocorticoid-induced osteoporosis

T Hou, L Zhang, X Yang - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Osteoporosis is a chronic disease whose symptoms include a reduction in bone strength,
osteopenia, and damage to the bone microstructure. Ferulic acids are natural polyphenols …

Delivery of the improved BMP-2-Advanced plasmid DNA within a gene-activated scaffold accelerates mesenchymal stem cell osteogenesis and critical size defect …

RM Raftery, I Mencía-Castaño, S Sperger… - Journal of controlled …, 2018 - Elsevier
Gene-activated scaffolds have been shown to induce controlled, sustained release of
functional transgene both in vitro and in vivo. Bone morphogenetic proteins (BMPs) are …

Cell-type targeted NF-kappaB inhibition for the treatment of inflammatory diseases

B Sehnert, H Burkhardt, S Dübel, RE Voll - Cells, 2020 - mdpi.com
Deregulated NF-k activation is not only involved in cancer but also contributes to the
pathogenesis of chronic inflammatory diseases like rheumatoid arthritis (RA) and multiple …