Inflammation is central to pathogenic processes in diabetes mellitus and the metabolic
syndrome and particularly implicates innate immunity in the development of complications …

The retinal pigment epithelium-photoreceptor interphase is renewed each day in a stunning
display of cellular interdependence. While photoreceptors use photosensitive pigments to …

Photoreceptors have high energy demands and a high density of mitochondria that produce
ATP through oxidative phosphorylation (OXPHOS) of fuel substrates. Although glucose is …

Diabetic retinopathy (DR) is a significant cause of vision loss and a research subject that is
constantly being explored for new mechanisms of damage and potential therapeutic options …

Acquired and inherited retinal disorders are responsible for vision loss in an increasing
proportion of individuals worldwide. Photoreceptor (PR) death is central to the vision loss …

Over a third of older adults in the US experience significant vision loss, which decreases
independence and is a biomarker of decreased health span. As the global aging population …

The eye is highly susceptible to inflammation-mediated tissue damage evoked during
bacterial infection. However, mechanisms regulating inflammation to protect the eye remain …

Leveraging linkage disequilibrium (LD) patterns as representative of population substructure
enables the discovery of additive association signals in genome-wide association studies …

There is a gap in understanding the effect of the essential ω-3 and ω-6 long-chain
polyunsaturated fatty acids (LCPUFA) on Phase I retinopathy of prematurity (ROP), which …

Abstract Docosahexaenoic acid (DHA, 22: 6n-3) accretion in brain phospholipids is critical
for maintaining the structural fluidity that permits proper assembly of protein complexes for …