Across neurodegenerative diseases, common mechanisms may reveal novel therapeutic
targets based on neuronal protection, repair, or regeneration, independent of etiology or site …

Glaucoma is a leading cause of irreversible blindness worldwide and is characterized by
progressive loss of visual function and retinal ganglion cells (RGC). Current …

Primary open-angle glaucoma (POAG), a leading cause of irreversible blindness globally,
shows disparity in prevalence and manifestations across ancestries. We perform meta …

Primary open-angle glaucoma (POAG) is a complex eye disease characterized by
progressive loss of optic nerve function that, if untreated, ultimately leads to irreversible …

Characterized by optic nerve atrophy due to retinal ganglion cell (RGC) death, glaucoma is
the leading cause of irreversible blindness worldwide. Of the major risk factors for glaucoma …

We examined the impact of 17β-estradiol (E2) eye drops on the modulation of the proteome
profile in the male rat retina. With discovery-driven proteomics, we have identified proteins …

Objective To explore the impact of the apolipoprotein E (APOE) E4 allele in the gender-
specific aging process in glaucoma by illustrating the interaction between risk factors …

Background Testosterone may be a possible modifiable risk factor for open-angle glaucoma
(OAG) and intraocular pressure (IOP), but evidence has been scarce and conflicting. In this …

Estrogen has emerged as a multifaceted signaling molecule in the retina, playing an
important role in neural development and providing neuroprotection in adults. It interacts …

This review explains that various hormones are chemical messengers affecting eyesight and
vision. Several factors, including side effects, hormonal changes during pregnancy, and …