The extracellular matrix (ECM) is a 3-dimensional structure and an essential component in
all human tissues. It is comprised of varying proteins, including collagens, elastin, and …

Systemic inflammation has been suggested to have a pivotal role in atherothrombosis, but
the factors that trigger systemic inflammation have not been fully elucidated …

Acidic pH of the skin surface has been recognized as a regulating factor for the maintenance
of the stratum corneum homeostasis and barrier permeability. The most important functions …

The emergence of drug-resistant bacteria calls for the discovery of new antibiotics. Yet, for
decades, traditional discovery strategies have not yielded new classes of antimicrobial …

Skin barrier dysfunction, a defining feature of atopic dermatitis (AD), arises from multiple
interacting systems. In AD, skin inflammation is caused by host–environment interactions …

Allergic diseases, such as respiratory, cutaneous, and food allergy, have dramatically
increased in prevalence over the last few decades. Recent research points to a central role …

The human skin is colonized by variety of microorganisms which, together with their
genomes and interactions with the host, constitute the human skin microbiome. In recent …

Skin is the largest organ in the human body, and the interplay between the environment
factors and human skin leads to some skin diseases, such as acne, psoriasis, and atopic …

Dermatological and cosmetics fields have recently started to focus on the human skin
microbiome and microbiota, since the skin microbiota is involved in the health and dysbiosis …

Acne is a chronic inflammatory disease of the pilosebaceous unit. Its pathophysiology
includes hyperseborrhoea, abnormal follicular keratinization and Propionibacterium acnes …