Cytotoxic meroterpenoids from brown alga Stypopodium schimperi (Kützing) Verlaque & Boudouresque with comprehensive molecular docking & dynamics and …

Ö Demirkıran, E Erol, H Şenol, İM Kesdi… - Process …, 2024 - Elsevier
In this study, five known meroterpenoids sargaol (1), flabellinone (2), stypodiol (3),
atomarianone A (4), atomarianone B (5), and a known steroid fucosterol (6) were isolated …

Synthesis of Sorafenib− Ruthenium Complexes, Investigation of Biological Activities and Applications in Drug Delivery Systems as an Anticancer Agent

B Zengin Kurt, D Öztürk Civelek… - Journal of Medicinal …, 2024 - ACS Publications
Sorafenib, a multiple kinase inhibitor, is widely used as a first-line treatment for
hepatocellular carcinoma. However, there is a need for more effective alternatives when …

Novel complex compounds of nickel with 3-(1-phenyl-2, 3-dimethyl-pyrazolone-5) azopentadione-2, 4: synthesis, NBO analysis, reactivity descriptors and in silico and …

S Tahirli, F Aliyeva, H Şenol… - Journal of …, 2024 - Taylor & Francis
A synthesized azo compound based on 4-amino antipyrine and its complexes with Ni (II) in
solution and solid phase is reported. The structures of these compounds have been testified …

New tetrahydro-isoquinoline derivatives as cholinesterase and α-glycosidase inhibitors: Synthesis, characterization, molecular docking & dynamics, ADME prediction …

I Mamedov, H Şenol, F Naghiyev, V Khrustalev… - Journal of Molecular …, 2024 - Elsevier
In the presented work, it was reported about the synthesis procedure of new isoquinoline
derivatives starting from chalcones and acetoacetanilide, a multi-step synthesis pathway …

Fe3O4 nanoparticles impregnated eggshell as an efficient biocatalyst for eco-friendly synthesis of 2-amino thiophene derivatives

M Zargari, HH Ardeshiri, H Ghafuri, MM Hassanzadeh - Heliyon, 2024 - cell.com
In this study, a biodegradable and eco-friendly biocatalyst (eggshell/Fe 3 O 4) was
synthesized utilizing eggshell impregnated with Fe 3 O 4 nanoparticles. The characterization …

Synthesis, Characterization, Crystal Structure, Molecular dynamics simulations, MM-GBSA analysis, and Bioactivity studies of pyrazine-and Pyrimidine-Modulated …

GG Abbasova, RH Ismayilov, DB Tagiyev… - Journal of Molecular …, 2024 - Elsevier
By using unsymmetrical pyrazine-and pyrimidine-modulated oligo-α-pyridylamine ligand N-
(4-methylpyrimidin-2-yl) pyrazin-2-amine (Hmpmpza)(1), 1D copper (II) coordination …

Synthesis of pyrrole-heterocyclic derivatives as anti-Alzheimer and antidiabetic candidates: An in vitro-in silico study

VP Ol'ga, DN Tomilin, H Şenol, KV Belyaeva… - Journal of Molecular …, 2024 - Elsevier
In this study, pyrrole-based heterocyclic compounds (2a-k) were synthesized and
characterized by elemental analysis, IR and NMR spectra. 11 representatives of the pyrrole …

4‐Furfuryloxymethyl‐1, 2, 3‐triazol‐1‐yl‐acetohydrazide Hybrids as Cholinesterase and Carbonic Anhydrase Inhibitors: Synthesis, Characterization and …

H Şenol - ChemistrySelect, 2024 - Wiley Online Library
This study focused on the synthesis and evaluation of the biological activity of ten novel
acetohydrazide hybrid derivatives, having furfuryloxy‐1, 2, 3‐triazole ring. All the target …