[HTML][HTML] Preparation, characterization, in-vitro and toxicological evaluation of carbopol based nanogels for solubility enhancement of Valsartan
M Suhail, MU Minhas, A Naeem, SF Badshah… - Applied Surface Science …, 2023 - Elsevier
Solubility is an essential criterion for attaining desired concentration of the drug within the
systemic circulation to ensure intended pharmacological action. The main setback for the …
systemic circulation to ensure intended pharmacological action. The main setback for the …
Self-emulsifying drug delivery system for oral anticancer therapy: Constraints and recent development
M Pandya, B Chatterjee, S Ganti - Current Pharmaceutical …, 2022 - ingentaconnect.com
Oral anticancer therapy faces several drawbacks: low aqueous solubility, poor and irregular
absorption from gastrointestinal sites, high first-pass metabolism, food-influenced …
absorption from gastrointestinal sites, high first-pass metabolism, food-influenced …
Dissolution and oral bioavailability enhancement of praziquantel by solid dispersions
Y Liu, T Wang, W Ding, C Dong, X Wang… - Drug delivery and …, 2018 - Springer
The aim of the present investigation was to enhance the solubility, dissolution, and oral
bioavailability of praziquantel (PZQ), a poorly water-soluble BCS II drug (Biopharmaceutical …
bioavailability of praziquantel (PZQ), a poorly water-soluble BCS II drug (Biopharmaceutical …
Preparation and appraisal of self-assembled valsartan-loaded amalgamated Pluronic F127/Tween 80 polymeric micelles: Boosted cardioprotection via regulation of …
HM Aboud, MO Mahmoud… - Journal of drug …, 2020 - Taylor & Francis
This study aimed to develop valsartan (VAL)-loaded mixed micelles and investigate their
cardioprotective potential and molecular mechanisms through Mhrt/Nrf2 and Trx1 pathways …
cardioprotective potential and molecular mechanisms through Mhrt/Nrf2 and Trx1 pathways …
Incorporating valsartan in sesame oil enriched self-nanoemulsifying system-loaded liquisolid tablets to improve its bioavailability
M Khalid, SH Alamri, HH Alsulimani, WS Alharbi… - International Journal of …, 2023 - Elsevier
Valsartan (VST) is a poorly soluble antihypertensive drug characterized by its limited
dissolution rate and low bioavailability. This study aims to improve VST solubility and …
dissolution rate and low bioavailability. This study aims to improve VST solubility and …
A Comprehensive Insight on Self Emulsifying Drug Delivery Systems
Background: The oral route is a highly recommended route for the delivery of a drug. But
most lipophilic drugs are difficult to deliver via this route due to their low aqueous solubility …
most lipophilic drugs are difficult to deliver via this route due to their low aqueous solubility …
Insights into the approach, fabrication, application, and lacunae of nanoemulsions in drug delivery systems
Many of the recently approved drug molecules that are therapeutically successful are found
to be incompatible for the development of a novel delivery system and to take part in various …
to be incompatible for the development of a novel delivery system and to take part in various …
[HTML][HTML] Integration of phospholipid-drug complex into self-nanoemulsifying drug delivery system to facilitate oral delivery of paclitaxel
D Ding, B Sun, W Cui, Q Chen, X Zhang… - Asian journal of …, 2019 - Elsevier
Self-nanoemulsifying drug delivery system (SNEDDS) has emerged as a promising platform
to improve oral absorption of drugs with poor solubility and low permeability. However, large …
to improve oral absorption of drugs with poor solubility and low permeability. However, large …
Optimization of solid self-dispersing micelle for enhancing dissolution and oral bioavailability of valsartan using Box-Behnken design
YT Goo, SY Park, BR Chae, HY Yoon, CH Kim… - International Journal of …, 2020 - Elsevier
A novel solid self-dispersing micelle (S-SDM) was developed to enhance the oral
bioavailability of valsartan (VST) and to reduce the total mass of solidified supersaturable …
bioavailability of valsartan (VST) and to reduce the total mass of solidified supersaturable …
[PDF][PDF] 缬沙坦胶囊联合醋酸泼尼松片治疗原发性肾病综合征患儿的疗效及对肾功能及炎性因子的影响
董君宇, 王勃, 贾玉涛, 张雪玲, 姜志红 - 现代生物医学进展, 2021 - biomed.cnjournals.com
摘要目的: 探讨原发性肾病综合征(NS) 患儿在醋酸泼尼松片治疗的基础上联合缬沙坦胶囊治疗
的临床疗效及对肾功能和炎性因子的影响. 方法: 选取2017 年2 月~ 2019 年4 …
的临床疗效及对肾功能和炎性因子的影响. 方法: 选取2017 年2 月~ 2019 年4 …