Gut microbiome–brain alliance: a landscape view into mental and gastrointestinal health and disorders

JM Sasso, RM Ammar, R Tenchov… - ACS Chemical …, 2023 - ACS Publications
Gut microbiota includes a vast collection of microorganisms residing within the
gastrointestinal tract. It is broadly recognized that the gut and brain are in constant …

The emerging role of bile acids in the pathogenesis of inflammatory bowel disease

JP Thomas, D Modos, SM Rushbrook… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic immune-mediated inflammatory disorder of
the gastrointestinal tract that arises due to complex interactions between host genetic risk …

Interactive relationships between intestinal flora and bile acids

X Guo, ES Okpara, W Hu, C Yan, Y Wang… - International Journal of …, 2022 - mdpi.com
The digestive tract is replete with complex and diverse microbial communities that are
important for the regulation of multiple pathophysiological processes in humans and …

[HTML][HTML] Herba Origani alleviated DSS-induced ulcerative colitis in mice through remolding gut microbiota to regulate bile acid and short-chain fatty acid metabolisms

Z Yu, D Li, H Sun - Biomedicine & Pharmacotherapy, 2023 - Elsevier
This study aimed to investigate the protective effect of Herba Origani, the dried whole herb of
Origanum vulgare L., on dextran sodium sulfate (DSS)-induced ulcerative colitis in mice and …

[HTML][HTML] Gut microbiome-produced metabolites in pigs: A review on their biological functions and the influence of probiotics

R Vasquez, JK Oh, JH Song… - Journal of Animal Science …, 2022 - ncbi.nlm.nih.gov
The gastrointestinal tract is a complex ecosystem that contains a large number of
microorganisms with different metabolic capacities. Modulation of the gut microbiome can …

New and emerging treatments for inflammatory bowel disease

M Higashiyama, R Hokari - Digestion, 2023 - karger.com
Background: The specific etiopathogenesis of inflammatory bowel disease (IBD) is still
unknown. Although the conventional anti-inflammatory or immunomodulatory drugs …

Microbiome and metabolome in inflammatory bowel disease

KG Upadhyay, DC Desai, TF Ashavaid… - Journal of …, 2023 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic gastrointestinal disease of unknown etiology,
involving complex interactions between the gut microbiome and host immune response. The …

Enterohaemorrhagic E. coli utilizes host- and microbiota-derived L-malate as a signaling molecule for intestinal colonization

B Liu, L Jiang, Y Liu, H Sun, J Yan, C Kang… - Nature …, 2023 - nature.com
The mammalian gastrointestinal tract is a complex environment that hosts a diverse
microbial community. To establish infection, bacterial pathogens must be able to compete …

The role of intestinal microbes on intestinal barrier function and host immunity from a metabolite perspective

Y Fu, J Lyu, S Wang - Frontiers in immunology, 2023 - frontiersin.org
The gut is colonized by many commensal microorganisms, and the diversity and metabolic
patterns of microorganisms profoundly influence the intestinal health. These microbial …

Pre-administration of berberine exerts chemopreventive effects in AOM/DSS-induced colitis-associated carcinogenesis mice via modulating inflammation and …

J Deng, L Zhao, X Yuan, Y Li, J Shi, H Zhang, Y Zhao… - Nutrients, 2022 - mdpi.com
Inflammatory activation and intestinal flora imbalance play an essential role in the
development and progression of colorectal cancer (CRC). Berberine (BBR) has attracted …