Machine intelligence in peptide therapeutics: A next‐generation tool for rapid disease screening

S Basith, B Manavalan, T Hwan Shin… - Medicinal research …, 2020 - Wiley Online Library
Discovery and development of biopeptides are time‐consuming, laborious, and dependent
on various factors. Data‐driven computational methods, especially machine learning (ML) …

Deep learning and ensemble deep learning for circRNA-RBP interaction prediction in the last decade: A review

D Lasantha, S Vidanagamachchi… - … Applications of Artificial …, 2023 - Elsevier
Circular ribonucleic acids (circRNAs) are widely expressed in cells and tissues and play vital
roles in cellular physiological processes. Their expressions are associated with …

DeepBIO: an automated and interpretable deep-learning platform for high-throughput biological sequence prediction, functional annotation and visualization analysis

R Wang, Y Jiang, J Jin, C Yin, H Yu… - Nucleic acids …, 2023 - academic.oup.com
Here, we present DeepBIO, the first-of-its-kind automated and interpretable deep-learning
platform for high-throughput biological sequence functional analysis. DeepBIO is a one-stop …

BioSeq-BLM: a platform for analyzing DNA, RNA and protein sequences based on biological language models

HL Li, YH Pang, B Liu - Nucleic acids research, 2021 - academic.oup.com
In order to uncover the meanings of 'book of life', 155 different biological language models
(BLMs) for DNA, RNA and protein sequence analysis are discussed in this study, which are …

BioSeq-Analysis2. 0: an updated platform for analyzing DNA, RNA and protein sequences at sequence level and residue level based on machine learning …

B Liu, X Gao, H Zhang - Nucleic acids research, 2019 - academic.oup.com
As the first web server to analyze various biological sequences at sequence level based on
machine learning approaches, many powerful predictors in the field of computational …

iLearnPlus: a comprehensive and automated machine-learning platform for nucleic acid and protein sequence analysis, prediction and visualization

Z Chen, P Zhao, C Li, F Li, D Xiang… - Nucleic acids …, 2021 - academic.oup.com
Sequence-based analysis and prediction are fundamental bioinformatic tasks that facilitate
understanding of the sequence (-structure)-function paradigm for DNAs, RNAs and proteins …

Improving protein-protein interactions prediction accuracy using XGBoost feature selection and stacked ensemble classifier

C Chen, Q Zhang, B Yu, Z Yu, PJ Lawrence… - Computers in biology …, 2020 - Elsevier
Protein-protein interactions (PPIs) are involved with most cellular activities at the proteomic
level, making the study of PPIs necessary to comprehending any biological process …

m5U-SVM: identification of RNA 5-methyluridine modification sites based on multi-view features of physicochemical features and distributed representation

C Ao, X Ye, T Sakurai, Q Zou, L Yu - BMC biology, 2023 - Springer
Abstract Background RNA 5-methyluridine (m5U) modifications are obtained by methylation
at the C5 position of uridine catalyzed by pyrimidine methylation transferase, which is …

BERT-Promoter: An improved sequence-based predictor of DNA promoter using BERT pre-trained model and SHAP feature selection

NQK Le, QT Ho, VN Nguyen, JS Chang - Computational Biology and …, 2022 - Elsevier
A promoter is a sequence of DNA that initializes the process of transcription and regulates
whenever and wherever genes are expressed in the organism. Because of its importance in …

A task-specific encoding algorithm for RNAs and RNA-associated interactions based on convolutional autoencoder

Y Wang, Z Pan, M Mou, W Xia, H Zhang… - Nucleic acids …, 2023 - academic.oup.com
RNAs play essential roles in diverse physiological and pathological processes by interacting
with other molecules (RNA/protein/compound), and various computational methods are …