Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

Sepsis is a multifactorial syndrome primarily determined by the host response to an invading
pathogen. It is common, with over 48 million cases worldwide in 2017, and often lethal. The …

Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2)-induced infection, the
cause of coronavirus disease 2019 (COVID-19), is characterized by unprecedented clinical …

Yes-associated protein (YAP) is a transcriptional co-activator that regulates cell proliferation
and survival by binding to a select set of enhancers for target gene activation. How YAP …

Microvascular dysfunction (MVD) is considered a crucial pathway in the development and
progression of cardiometabolic and renal disease and is associated with increased …

Sepsis remains a major medical challenge, for which, apart from improvements in supportive
care, treatment has not relevantly changed over the last few decades. Vasodilation and …

Microtissues with specific structures and integrated vessels play a key role in maintaining
organ functions. To recapitulate the in vivo environment for tissue engineering and organ-on …

Successful pregnancy and reproduction are dependent on adequate uterine blood flow,
placental perfusion, and vascular responsivity to fetal demands. The ability to support …

Microvascular networks play key roles in oxygen transport and nutrient delivery to meet the
varied and dynamic metabolic needs of different tissues throughout the body, and their …

Asthma is an inflammatory disease of the lung airway network, which is initiated and
perpetuated by allergen-specific CD4+ T cells, IgE antibodies, and a massive release of Th2 …