In recent decades, immune checkpoint blockade and chimeric antigen receptor T cell (CAR-
T) therapy are two milestone achievements in clinical immunotherapy. However, both show …

Tumor-infiltrating lymphocytes (TILs), frontline soldiers of the adaptive immune system, are
recruited into the tumor site to fight against tumors. However, their small number and …

Colorectal cancer (CRC) is a serious public health issue, and it has the leading incidence
and mortality among malignant tumors worldwide. CRC patients with metastasis in the liver …

Today, it is well-known that the interactions and secretion within the tumour are crucial to
consider for cancer therapy. Some novel cancer therapy modalities such as immunotherapy …

With cancer incidence rates continuing to increase and occurrence of resistance in drug
treatment, there is a pressing demand to find safer and more effective anticancer strategy for …

Icariin (ICA) is a kind of natural flavonoid compound monomer, which is derived from the
extract of dried stems and leaves of Epimedium. Modern pharmacological studies have …

Colorectal cancer (CRC) is the third most common cancer in the world. Although there are
standard treatment options for CRC, most patients respond poorly to these treatments …

Macrophages are one of the first innate immune cells to reach the site of infection or injury.
Diverse functions from the uptake of pathogen or antigen, its killing, and presentation, the …

The intricate molecular landscape of cancer pathogenesis continues to captivate
researchers worldwide, with Circular RNAs (circRNAs) emerging as pivotal players in the …

Immunotherapy has transformed treatment for various types of malignancy. However, the
benefit of immunotherapy is limited to a minority of patients with mismatch-repair-deficient …