Understanding cell‐cell communication and signaling in the colorectal cancer microenvironment
Carcinomas are complex heterocellular systems containing epithelial cancer cells, stromal
fibroblasts, and multiple immune cell‐types. Cell‐cell communication between these tumor …
fibroblasts, and multiple immune cell‐types. Cell‐cell communication between these tumor …
Radiopharmaceuticals: navigating the frontier of precision medicine and therapeutic innovation
This review article explores the dynamic field of radiopharmaceuticals, where innovative
developments arise from combining radioisotopes and pharmaceuticals, opening up …
developments arise from combining radioisotopes and pharmaceuticals, opening up …
Patient-derived organoids as a model for cancer drug discovery
In the search for the ideal model of tumours, the use of three-dimensional in vitro models is
advancing rapidly. These are intended to mimic the in vivo properties of the tumours which …
advancing rapidly. These are intended to mimic the in vivo properties of the tumours which …
Transcending toward advanced 3D-cell culture modalities: a review about an emerging paradigm in translational oncology
Cancer is a disorder characterized by an uncontrollable overgrowth and a fast-moving
spread of cells from a localized tissue to multiple organs of the body, reaching a metastatic …
spread of cells from a localized tissue to multiple organs of the body, reaching a metastatic …
GRPR-targeting radiotheranostics for breast cancer management
A D'Onofrio, S Engelbrecht, T Läppchen… - Frontiers in …, 2023 - frontiersin.org
Breast Cancer (BC) is the most common cancer worldwide and, despite the advancements
made toward early diagnosis and novel treatments, there is an urgent need to reduce its …
made toward early diagnosis and novel treatments, there is an urgent need to reduce its …
Models for translational proton radiobiology—from bench to bedside and back
T Suckert, S Nexhipi, A Dietrich, R Koch… - Cancers, 2021 - mdpi.com
Simple Summary An increasing number of cancer patients are treated with proton therapy.
Nevertheless, there are still open questions that require preclinical studies, for example …
Nevertheless, there are still open questions that require preclinical studies, for example …
[HTML][HTML] Molecular alterations in pancreatic tumors
M Visani, G Acquaviva, A De Leo, V Sanza… - World journal of …, 2021 - ncbi.nlm.nih.gov
Genetic alterations in pancreatic tumors can usually be classified in:(1) Mutational activation
of oncogenes;(2) Inactivation of tumor suppressor genes; and (3) Inactivation of genome …
of oncogenes;(2) Inactivation of tumor suppressor genes; and (3) Inactivation of genome …
Integration of organoids in peptide drug discovery: Rise of the high‐throughput screening
S Zhang, J Shen, X Wang, X Sun, Y Wu, MR Zhang… - View, 2023 - Wiley Online Library
Organoids are three‐dimensional cell aggregates with near‐physiologic cell behaviors and
can undergo long‐term expansion in vitro. They are amenable to high‐throughput drug …
can undergo long‐term expansion in vitro. They are amenable to high‐throughput drug …
Enhanced radiotherapy efficacy of breast cancer multi cellular tumor spheroids through in-situ fabricated chitosan-zinc oxide bio-nanocomposites as radio-sensitizing …
Overwhelming evidence has shown that three-dimensional multicellular tumor spheroids
(MCTSs) as a mimic of in-vivo tumor can accurately exhibit cellular responses to treatments …
(MCTSs) as a mimic of in-vivo tumor can accurately exhibit cellular responses to treatments …
Surface-fabrication of fluorescent hydroxyapatite for cancer cell imaging and bio-printing applications
Hydroxyapatite (HAP) materials are widely applied as biomedical materials due to their
stable performance, low cost, good biocompatibility and biodegradability. Here, a green, fast …
stable performance, low cost, good biocompatibility and biodegradability. Here, a green, fast …