Essential hypertension, a multifaceted disorder, is a worldwide health problem. A complex
network of genetic, epigenetic, physiological, and environmental components regulates …

Maternal mortality rates in the United States have steadily increased since 1987 to the
current rate of over 16 deaths per 100,000 live births. Whereas most of these deaths are …

Dementia affects almost 50 million adults worldwide, and remains a major cause of death
and disability. Hypertension is a leading risk factor for dementia, including Alzheimer …

Elevated blood pressure is a well-established risk factor for age-related cognitive decline.
Long linked to cognitive impairment on vascular bases, increasing evidence suggests a …

Inflammation and activation of the immune system are key molecular and cellular events in
the pathogenesis of cardiovascular diseases, including atherosclerosis, hypertension …

Hypertension is one of the most prevalent and powerful contributors of cardiovascular
diseases. Malignant hypertension is a relatively rare but extremely severe form of …

Background: Circadian rhythms play an essential role in physiological function. The
molecular clock that underlies circadian physiological function consists of a core group of …

Cardiovascular disease is a primary cause of mortality worldwide, and patients often require
bypass surgery that utilizes autologous vessels as conduits. However, the limited availability …

The rat has been extensively used as a small animal model. Many genetically engineered
rat models have emerged in the last two decades, and the advent of gene-specific …

VGINYW is a highly active angiotensin I-converting enzyme (ACE) inhibitory peptide
discovered from α-lactalbumin by an in vitro–in silico high throughput screening strategy …