Introduction: Aging has many effects on the cardiovascular system, including changes in
structure (aortic composition, and thus stiffening) and function (increased proximal blood …

Comorbidities of ischemic heart disease, including diabetes mellitus (DM),
hypercholesterolemia (HC) and chronic kidney disease (CKD), are associated with coronary …

Benign prostatic hyperplasia (BPH) and associated lower urinary tract symptoms are
common clinical concerns that affect aging men all over the world. The underlying molecular …

Aim Sexual dimorphisms are evident along the nephron: Females (F) exhibit higher ratios of
renal distal to proximal Na+ transporters' abundance, greater lithium clearance (CLi) more …

Hypertension is associated with endothelial dysfunction and decreased nitric oxide (NO). It
has been proposed that decreasing oxidative stress may help regulate blood pressure by …

Galectin-3 (Gal-3) is a carbohydrate-binding protein with multiple functions. Gal-3 regulates
cell growth, proliferation, and apoptosis by orchestrating cell-cell and cell-matrix interactions …

This white paper is the outcome of the seventh UC Davis Cardiovascular Research
Symposium on Systems Approach to Understanding Cardiovascular Disease and …

Introduction Considerable evidence has linked periodontitis (PD) to hypertension (HTN), but
the nature behind this connection is unclear. Dysbiosis of oral microbiota leading to PD is …

The National Heart, Lung, and Blood Institute convened a multidisciplinary working group of
hypertension researchers on December 6 to 7, 2018, in Bethesda, MD, to share current …

Aims Dysregulated immune response contributes to inefficiency of treatment strategies to
control hypertension and reduce the risk of end-organ damage. Uncovering the immune …