Immunoengineering biomaterials for musculoskeletal tissue repair across lifespan
Musculoskeletal diseases and injuries are among the leading causes of pain and morbidity
worldwide. Broad efforts have focused on developing pro‐regenerative biomaterials to treat …
worldwide. Broad efforts have focused on developing pro‐regenerative biomaterials to treat …
Injectable Inflammation‐Responsive Hydrogels for Microenvironmental Regulation of Intervertebral Disc Degeneration
L Liu, W Wang, L Huang, Y Xian, W Ma… - Advanced …, 2024 - Wiley Online Library
Chronic local inflammation and excessive cell apoptosis in nucleus pulposus (NP) tissue are
the main causes of intervertebral disc degeneration (IDD). Stimuli‐responsive hydrogels …
the main causes of intervertebral disc degeneration (IDD). Stimuli‐responsive hydrogels …
Effective delivery of miR-150-5p with nucleus pulposus cell-specific nanoparticles attenuates intervertebral disc degeneration
H Jiang, H Qin, Q Yang, L Huang, X Liang… - Journal of …, 2024 - Springer
Background The use of gene therapy to deliver microRNAs (miRNAs) has gradually
translated to preclinical application for the treatment of intervertebral disc degeneration …
translated to preclinical application for the treatment of intervertebral disc degeneration …
Thermosensitive composite hydrogel with antibacterial, immunomodulatory, and osteogenic properties promotes periodontal bone regeneration via staged release of …
X Wang, Q Li, Z Liu, Y Wu, Z Zhang, J Mao… - Materials Today …, 2024 - Elsevier
Periodontitis is a common type of inflammatory bone loss induced by bacterial infection in
tooth-supporting tissue. Effective bone regeneration in the inflammatory microenvironment of …
tooth-supporting tissue. Effective bone regeneration in the inflammatory microenvironment of …
The Sanbi Decoction alleviates intervertebral disc degeneration in rats through intestinal flora and serum metabolic homeostasis modulation
N Wang, S Chen, Y Xie, X Liu, Z Xi, J Li, C Xue, R Deng… - Phytomedicine, 2024 - Elsevier
Background Intervertebral disc degeneration (IVDD) is an essential cause of low back pain
(LBP), the incidence of which has risen in recent years and is progressively younger, but …
(LBP), the incidence of which has risen in recent years and is progressively younger, but …
Immunization against nucleus pulposus antigens to accelerate degenerative disc disease in a rabbit model
Low back pain poses a significant societal burden, with progressive intervertebral disc
degeneration (IDD) emerging as a pivotal contributor to chronic pain. Improved animal …
degeneration (IDD) emerging as a pivotal contributor to chronic pain. Improved animal …
The MnO2/GelMA Composite Hydrogels Improve the ROS Microenvironment of Annulus Fibrosus Cells by Promoting the Antioxidant and Autophagy through the …
B Xu, M Huang, J Li, Q Meng, J Hu, Q Chen, H He… - Gels, 2024 - mdpi.com
Intervertebral disc degeneration (IVDD) is a worldwide disease that causes low back pain
and reduces quality of life. Biotherapeutic strategies based on tissue engineering …
and reduces quality of life. Biotherapeutic strategies based on tissue engineering …