Digestive tumours, a common kind of malignancy worldwide, have recently led to the most
tumour-related deaths. Angiogenesis, the process of forming novel blood vessels from pre …

Solid tumors are composed of a highly complex and heterogenic microenvironment, with
increasing metabolic status. This environment plays a crucial role in the clinical therapeutic …

Background Abnormal function or overexpression of CD73 and EZH2 within the tumor
microenvironment and tumor cells enhances tumor growth and progression, and in many …

Melanoma is the most aggressive form of skin cancer resulting from genetic mutations in
melanocytes. Several factors have been considered to be involved in melanoma …

Epithelial–mesenchymal transition (EMT), a physiological process during embryogenesis,
can become pathological in the presence of different driving forces. Reduced oxygen …

Primary and metastatic lung cancers are malignant lung tumors each with of which has a
different pathogenesis, although both threaten patient lives. Tumor development and …

Prevention of drug resistance is a significant challenge in treating Acute Lymphoblastic
Leukemia. It has been demonstrated that activating DNA Damage Repair (DDR) pathways …

Purpose Non-small-cell lung cancer (NSCLC) is a major public health concern with a high
incidence worldwide. Coal-derived fulvic acids (FAs) contain functional groups in their …

Hypoxia-inducible factor (HIF), which plays a crucial role in oxygen homeostasis, contributes
to immunosuppression, tumor angiogenesis, multidrug resistance, photodynamic therapy …

Photodynamic therapy (PDT) is a promising alternative approach to improve the treatment of
several diseases. PDT can also be used in combination with other therapies. The success of …