Recommendations for the prophylactic management of skin reactions induced by epidermal growth factor receptor inhibitors in patients with solid tumors

RD Hofheinz, G Deplanque, Y Komatsu… - The …, 2016 - academic.oup.com
Inhibition of the epidermal growth factor receptor (EGFR) is an established treatment that
extends patient survival across a variety of tumor types. EGFR inhibitors fall into two main …

Tetracycline antibiotics: Potential anticancer drugs

J Li, Y Qin, C Zhao, Z Zhang, Z Zhou - European journal of pharmacology, 2023 - Elsevier
In recent years, research on tetracycline antibiotics has gradually shifted from their
antibacterial effects to anticancer effects. Doxycycline, minocycline, and tigecycline as the …

mRNA–miRNA bipartite network reconstruction to predict prognostic module biomarkers in colorectal cancer stage differentiation

H Motieghader, M Kouhsar, A Najafi, B Sadeghi… - Molecular …, 2017 - pubs.rsc.org
Biomarker detection is one of the most important and challenging problems in cancer
studies. Recently, non-coding RNA based biomarkers such as miRNA expression levels …

The impact of long-term antibiotic therapy of cutaneous adverse reactions to EGFR inhibitors in colorectal cancer patients

MM Mihai, A Ion, C Giurcăneanu, C Nițipir… - Journal of Clinical …, 2021 - mdpi.com
Colorectal cancer (CRC) is an important public health issue, in terms of incidence and
mortality, with approximately 1.8 million new cases reported worldwide in 2018 …

Antibiotic prophylaxis for skin toxicity induced by antiepidermal growth factor receptor agents: a systematic review and meta‐analysis

F Petrelli, K Borgonovo, M Cabiddu… - British Journal of …, 2016 - academic.oup.com
Topical and systemic prophylactic measures, which are administered before the
development of epidermal growth factor receptor (EGFR)‐related acneiform rash, are …

EGFR inhibitors and cutaneous complications: a practical approach to management

LM Guggina, AW Choi, JN Choi - Oncology and Therapy, 2017 - Springer
Epidermal growth factor receptor inhibitors (EGFRIs) are increasingly being used for
malignancies of epithelial origin. Though these therapies are better tolerated than …

Risk factor analysis for anti-epidermal growth factor receptor monoclonal antibody–induced skin toxicities in real-world metastatic colorectal cancer treatment

Y Saito, K Uchiyama, Y Takekuma, Y Komatsu… - Supportive Care in …, 2023 - Springer
Purpose Anti-epidermal growth factor receptor (anti-EGFR) monoclonal antibodies are
effective in treating RAS wild-type metastatic colorectal cancer (mCRC). However, their …

Update review of skin adverse events during treatment of lung cancer and colorectal carcinoma with epidermal growth receptor factor inhibitors

Y Peng, Q Li, J Zhang, W Shen, X Zhang, C Sun… - BioScience …, 2018 - jstage.jst.go.jp
The past decades have witnessed a rapid increase in the use of molecularly targeted
therapies. One class of agents includes the epidermal growth factor receptor inhibitors …

[HTML][HTML] ONS Guidelines™ for cancer treatment–related skin toxicity

LA Williams - Number 5/September 2020, 2020 - onf.ons.org
Background: Management of cancer treatment–related skin toxicities can minimize treatment
disruptions and improve patient well-being. Objectives: This guideline aims to support …

Current recommendations and novel strategies for the management of skin toxicities related to anti-EGFR therapies in patients with metastatic colorectal cancer

MC Annunziata, A De Stefano, G Fabbrocini… - Clinical Drug …, 2019 - Springer
The use of targeted therapies, when added to conventional chemotherapy, has significantly
improved clinical outcomes and survival of cancer patients. While targeted therapies do not …