[HTML][HTML] Effects of terpenes in the treatment of visceral leishmaniasis: A systematic review of preclinical evidence
VD Raimundo, RPR Carvalho… - Pharmacological …, 2022 - Elsevier
Visceral leishmaniasis (VL) is a severe and potentially fatal neglected tropical disease,
being considered a public health concern in many countries worldwide. There are still no …
being considered a public health concern in many countries worldwide. There are still no …
Road‐map of pre‐clinical treatment for Visceral Leishmaniasis
P Mazire, V Agarwal, A Roy - Drug Development Research, 2022 - Wiley Online Library
Visceral leishmaniasis (VL) or Kala‐azar, is the most lethal form of leishmaniasis, is still
prevalent in many countries where it is endemic. It is a threat to human life caused by …
prevalent in many countries where it is endemic. It is a threat to human life caused by …
Impact of visceral leishmaniasis on local organ metabolism in hamsters
Leishmania is an intracellular parasite with different species pathogenic to humans and
causing the disease leishmaniasis. Leishmania donovani causes visceral leishmaniasis …
causing the disease leishmaniasis. Leishmania donovani causes visceral leishmaniasis …
Protective efficacy in a Hamster model of a multivalent vaccine for human visceral Leishmaniasis (MuLeVaClin) consisting of the KMP11, LEISH-F3+, and LJL143 …
L Fernández, JC Solana, C Sánchez, MÁ Jiménez… - Microorganisms, 2021 - mdpi.com
Visceral leishmaniasis (VL) is the most severe clinical form of leishmaniasis, fatal if
untreated. Vaccination is the most cost-effective approach to disease control; however, to …
untreated. Vaccination is the most cost-effective approach to disease control; however, to …
Status of IL‐4 and IL‐10 driven markers in experimental models of Visceral Leishmaniasis
Aim Leishmania donovani, the causative agent for visceral leishmaniasis (VL), modulates
host monocytes/macrophages to ensure its survival. However, knowledge regarding the host …
host monocytes/macrophages to ensure its survival. However, knowledge regarding the host …
Bioluminescent Imaging Identifies Thymus, As Overlooked Colonized Organ, in a Chronic Model of Leishmania donovani Mouse Visceral Leishmaniasis
B Dominguez-Asenjo, C Gutierrez-Corbo… - ACS Infectious …, 2021 - ACS Publications
The search for new drugs against neglected parasitic diseases has experienced a major
boost in recent years with the incorporation of bioimaging techniques. Visceral …
boost in recent years with the incorporation of bioimaging techniques. Visceral …
Assay development in leishmaniasis drug discovery: a comprehensive review
B Zulfiqar, VM Avery - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
Introduction Cutaneous, muco-cutaneous and visceral leishmaniasis occur due to an
infection with the protozoan parasite Leishmania. The current therapeutic options are limited …
infection with the protozoan parasite Leishmania. The current therapeutic options are limited …
[HTML][HTML] Evolving immunometabolic response to the early Leishmania infantum infection in the spleen of BALB/c mice described by gene expression profiling
G Palacios, R Diaz-Solano, B Valladares… - Acta Tropica, 2023 - Elsevier
Transcriptional analysis is a useful approximation towards the identification of global
changes in host-pathogen interaction, in order to elucidate tissue-specific immune …
changes in host-pathogen interaction, in order to elucidate tissue-specific immune …
Quantitative monitoring of experimental and human leishmaniasis employing amastigote-specific genes
M Roy, D Sarkar, M Chatterjee - Parasitology, 2022 - cambridge.org
The gold standard for diagnosis of leishmaniasis is the microscopic detection of
amastigotes/Leishman Donovan (LD) bodies, but its moderate sensitivity necessitates the …
amastigotes/Leishman Donovan (LD) bodies, but its moderate sensitivity necessitates the …
Immunoprophylaxis using polypeptide chimera vaccines plus adjuvant system promote Th1 response controlling the spleen parasitism in hamster model of visceral …
MR Gusmão, TLVDP Ostolin, LM Carvalho, AFP Costa… - Vaccine, 2022 - Elsevier
In recent years, several advances have been observed in vaccinology especially for
neglected tropical diseases (NTDs). One of the tools employed is epitope prediction by …
neglected tropical diseases (NTDs). One of the tools employed is epitope prediction by …