Temperature-and pH-responsive injectable chitosan hydrogels loaded with doxorubicin and curcumin as long-lasting release platforms for the treatment of solid …

N Li, J Lin, C Liu, Q Zhang, R Li, C Wang… - … in Bioengineering and …, 2022 - frontiersin.org
The efficacy of treating solid tumors with chemotherapy is primarily hindered by dose-limiting
toxicity due to off-target effects and the heterogeneous drug distribution caused by the dense …

Fabrication of a multi-level drug release platform with liposomes, chitooligosaccharides, phospholipids and injectable chitosan hydrogel to enhance anti-tumor …

R Li, Y Lyu, S Luo, H Wang, X Zheng, L Li, N Ao… - Carbohydrate …, 2021 - Elsevier
Some anti-cancer drugs have poor solubility and availability, and are easily eliminated by
rapid metabolism in vivo. To fix the drugs at the administration site and delay their release, a …

[HTML][HTML] Self-assembled bilosomes with stimuli-responsive properties as bioinspired dual-tunable nanoplatform for pH/temperature-triggered release of hybrid cargo

E Waglewska, A Pucek-Kaczmarek… - Colloids and Surfaces B …, 2022 - Elsevier
The rapid development of colloid chemistry has raised the possibility of using nanocarriers
for the targeted delivery and the controlled drug release at predictable locations to reduce …

The formation of chitosan-coated rhamnolipid liposomes containing curcumin: stability and in vitro digestion

W Zhou, C Cheng, L Ma, L Zou, W Liu, R Li, Y Cao… - Molecules, 2021 - mdpi.com
There is growing interest in developing biomaterial-coated liposome delivery systems to
improve the stability and bioavailability of curcumin, which is a hydrophobic nutraceutical …

Fbs-derived exosomes as a natural nano-scale carrier for icariin promote osteoblast proliferation

M Dong, S Wu, H Xu, X Yu, L Wang, H Bai… - … in Bioengineering and …, 2021 - frontiersin.org
Icariin is a class IV drug of low solubility, permeability, and poor bioavailability. Synthetic
nanomaterials have developed rapidly. However, some literatures point out that synthetic …

Recent advance of nanoparticle-based topical drug delivery to the posterior segment of the eye

Y Wang, X Xu, Y Gu, Y Cheng, F Cao - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Considering that the number of patients afflicted by posterior eye diseases is
increasing, effective drug delivery is currently in high clinical demand. Topical administration …

Novel chitosan-silica hybrid hydrogels for cell encapsulation and drug delivery

SN Jayash, PR Cooper, RM Shelton… - International journal of …, 2021 - mdpi.com
Hydrogels constructed from naturally derived polymers provide an aqueous environment
that encourages cell growth, however, mechanical properties are poor and degradation can …

Middle purity soy lecithin is appropriate for food grade nanoliposome: Preparation, characterization, antioxidant and anti-inflammatory ability

J Li, J Nan, H Wu, HJ Park, Q Zhao, L Yang - Food Chemistry, 2022 - Elsevier
The purity of soy lecithin exerts significant impact on nanoliposome (NL) properties for food
applications. In this study, three soy lecithin of different purity were used to prepare NL. LC …

The influence of sodium alginate and genipin on physico-chemical properties and stability of WPI coated liposomes

AZ Ghaleshahi, G Rajabzadeh - Food research international, 2020 - Elsevier
In this work, coated liposome as a novel delivery system assembled from genipin-
crosslinked with whey protein isolate (WPI) and sodium alginate (SA) as the second layer on …

'Sweet as a Nut': Production and use of nanocapsules made of glycopolymer or polysaccharide shell

X Yan, L Chai, E Fleury, F Ganachaud… - Progress in Polymer …, 2021 - Elsevier
Polymeric nanomaterials are deemed to unlock the potential of therapeutics and improve
their efficiency, to allow future advances in nanomedicine. Among these, sugar-based …