Oxidative stress, inflammation, and vascular aging in hypertension
TJ Guzik, RM Touyz - Hypertension, 2017 - Am Heart Assoc
Guzik and Touyz Oxidation and Inflammation in Vascular Aging 661 and endothelium. 22
Perivascular fibrosis is greatly dependent on immune cells because it is prevented in …
Perivascular fibrosis is greatly dependent on immune cells because it is prevented in …
The aging cardiovascular system: understanding it at the cellular and clinical levels
Cardiovascular disease (CVD) presents a great burden for elderly patients, their caregivers,
and health systems. Structural and functional alterations of vessels accumulate throughout …
and health systems. Structural and functional alterations of vessels accumulate throughout …
Host and environmental factors influencing individual human cytokine responses
R Ter Horst, M Jaeger, SP Smeekens, M Oosting… - Cell, 2016 - cell.com
Differences in susceptibility to immune-mediated diseases are determined by variability in
immune responses. In three studies within the Human Functional Genomics Project, we …
immune responses. In three studies within the Human Functional Genomics Project, we …
Ageing, metabolism and cardiovascular disease
S Costantino, F Paneni… - The Journal of physiology, 2016 - Wiley Online Library
Age is one of the major risk factors associated with cardiovascular disease (CVD). About
one‐fifth of the world population will be aged 65 or older by 2030, with an exponential …
one‐fifth of the world population will be aged 65 or older by 2030, with an exponential …
[HTML][HTML] Ageing as a risk factor for disease
T Niccoli, L Partridge - Current biology, 2012 - cell.com
Age is the main risk factor for the prevalent diseases of developed countries: cancer,
cardiovascular disease and neurodegeneration. The ageing process is deleterious for …
cardiovascular disease and neurodegeneration. The ageing process is deleterious for …
Signaling pathways involved in vascular smooth muscle cell calcification during hyperphosphatemia
J Voelkl, F Lang, KU Eckardt, K Amann… - Cellular and Molecular …, 2019 - Springer
Medial vascular calcification has emerged as a putative key factor contributing to the
excessive cardiovascular mortality of patients with chronic kidney disease (CKD) …
excessive cardiovascular mortality of patients with chronic kidney disease (CKD) …
Molecular biology of atherosclerosis
PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …
Basic biology of oxidative stress and the cardiovascular system: part 1 of a 3-part series
The generation of reactive oxygen species (ROS) is a fundamental aspect of normal human
biology. However, when ROS generation exceeds endogenous antioxidant capacity …
biology. However, when ROS generation exceeds endogenous antioxidant capacity …
Mechanistic insights into vascular calcification in CKD
Cardiovascular disease begins early in the course of renal decline and is a life-limiting
problem in patients with CKD. The increased burden of cardiovascular disease is due, at …
problem in patients with CKD. The increased burden of cardiovascular disease is due, at …
Cellular and molecular biology of aging endothelial cells
Cardiovascular disease (CVD) is the leading cause of death in the United States and aging
is a major risk factor for CVD development. One of the major age-related arterial phenotypes …
is a major risk factor for CVD development. One of the major age-related arterial phenotypes …