Objective Deep brain stimulation (DBS) of the ventral internal capsule/striatum (VCVS) is a
potentially effective treatment for several mental health disorders when conventional …

The 10th annual DBS Think Tank had a theme of women leaders in neuromodulation and
Dr. Helen Mayberg was the invited keynote speaker. In her talk, Dr. Mayberg emphasized …

A large fraction of patients with mental disorders obtain no relief from medications,
psychotherapy, or noninvasive treatments. For these patients, deep brain stimulation (DBS) …

Closed-loop approaches in systems neuroscience and therapeutic stimulation have the
potential to revolutionize our understanding of the brain and develop novel neuromodulation …

Most patients with Parkinson's disease (PD) are treated with medication, and a multitude of
dopamine-enhancing agents is available as the therapeutic option (Armstrong and Okun …

1. Methods Two patients implanted with Medtronic's Percept PC™ to treat Parkinson's
Disease provided informed consent before participating in this study (Lifespan# 1160521) …

METHODS: We rely on diffusion tractography when planning stereotactic targets for 3 of 5
anatomic areas. We outline the rationale and fiber tracts that we focus on for targeting …

ABSTRACT A prominent electrophysiological feature of compulsive behaviours is striatal
hyperactivity; but its underlying dysfunctional cellular mechanisms still need to be …

I would like to thank my promotor Bart Preneel for the support, guidance and the valuable
feedback. My sincere gratitude also goes to Eduard Marin and Dave Singelée for providing …