Integration between tendon/ligament and bone occurs through a specialized tissue interface
called enthesis. The complex and heterogeneous structure of the enthesis is essential to …

The last decade has seen significant developments in cell therapies, based on permanently
differentiated, reprogrammed or engineered stem cells, for tendon injuries and degenerative …

Topographical cues from the extracellular microenvironment can influence cellular activity
including proliferation and differentiation. Information on the effects of material topography …

Human embryonic stem cells (hESC) and their differentiated progenies are an attractive cell
source for transplantation therapy and tissue engineering. Nevertheless, the utility of these …

Mesenchymal stem cells (MSCs) have the potential to replace or restore the function of
damaged tissues and offer much promise in the successful application of tissue engineering …

The development of tendon-biomimetic nanofibrous scaffolds with mesenchymal stem cells
may represent a promising strategy to improve the unsatisfactory outcomes of traditional …

As tendon stem/progenitor cells were reported to be rare in tendon tissues, tendons as
vulnerable targets of sports injury possess poor self-repair capability. Human ESCs (hESCs) …

Tendon injury is the most common disease in the musculoskeletal system. The current
treatment methods have many limitations, such as poor therapeutic effects, functional loss of …

Although many studies have demonstrated that cell phenotype is affected by the surface
properties of biomaterials, these materials often fail to mimic the complexity of the native …

Tendon/ligament injuries are very common in sports and other rigorous activities. Tendons
regenerate and repair slowly and inefficiently in vivo after injury. The limited ability of tendon …