Summary Response Assessment in Neuro-Oncology (RANO) response criteria have been
established and were updated in 2023 for MRI-based response evaluation of diffuse …

Translocator protein (TSPO) is involved in several cellular mechanisms such as
steroidogenesis, immunomodulation, cell proliferation and differentiation. Overexpressed in …

Various cellular sources hamper interpretation of positron emission tomography (PET)
biomarkers in the tumor microenvironment (TME). We developed an approach of …

Abstract Purpose According to the World Health Organization classification for tumors of the
central nervous system, mutation status of the isocitrate dehydrogenase (IDH) genes has …

Local therapy strategies still provide only limited success in the treatment of glioblastoma,
the most frequent primary brain tumor in adults, indicating global involvement of the brain in …

Despite continuing efforts to find new therapeutic strategies for glioblastoma, the prognosis
of affected patients remains poor. Tumor recurrence is an unfortunate reality, largely due to …

Conventional MRI sequences are standard methods to monitor patients with brain tumors
but have significant limitations especially after irradiation. Currently, the role of FET-PET in …

The 18-kDa translocator protein (TSPO) is a protein of the outer mitochondrial membrane.
Due to its location, it has been associated with key cellular functions. It has been shown that …

Es wird zunehmend deutlich, dass Gliome eine heterogene Gruppe komplexer Tumortypen
sind, die entsprechend ihren distinkten molekularen Profilen individuell angepasster …