Early-life interactions between the microbiota and immune system: impact on immune system development and atopic disease
Prenatal and early postnatal life represent key periods of immune system development. In
addition to genetics and host biology, environment has a large and irreversible role in the …
addition to genetics and host biology, environment has a large and irreversible role in the …
Immune-microbe interactions early in life: A determinant of health and disease long term
P Brodin - Science, 2022 - science.org
Research on newborn immunity has revealed the importance of cell ontogeny, feto-maternal
tolerance, and the transfer of maternal antibodies. Less is known about postnatal adaptation …
tolerance, and the transfer of maternal antibodies. Less is known about postnatal adaptation …
Multi-omics analyses of airway host–microbe interactions in chronic obstructive pulmonary disease identify potential therapeutic interventions
Z Yan, B Chen, Y Yang, X Yi, M Wei… - Nature …, 2022 - nature.com
The mechanistic role of the airway microbiome in chronic obstructive pulmonary disease
(COPD) remains largely unexplored. We present a landscape of airway microbe–host …
(COPD) remains largely unexplored. We present a landscape of airway microbe–host …
[HTML][HTML] Microbiome-based interventions to modulate gut ecology and the immune system
The gut microbiome lies at the intersection between the environment and the host, with the
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …
Postbiotics as the new frontier in food and pharmaceutical research
S Sabahi, A Homayouni Rad… - Critical reviews in …, 2023 - Taylor & Francis
Food is the essential need of human life and has nutrients that support growth and health.
Gastrointestinal tract microbiota involves valuable microorganisms that develop therapeutic …
Gastrointestinal tract microbiota involves valuable microorganisms that develop therapeutic …
[HTML][HTML] An early-life microbiota metabolite protects against obesity by regulating intestinal lipid metabolism
The mechanisms by which the early-life microbiota protects against environmental factors
that promote childhood obesity remain largely unknown. Using a mouse model in which …
that promote childhood obesity remain largely unknown. Using a mouse model in which …
Priority effects shape the structure of infant-type Bifidobacterium communities on human milk oligosaccharides
Bifidobacteria are among the first colonizers of the infant gut, and human milk
oligosaccharides (HMOs) in breastmilk are instrumental for the formation of a bifidobacteria …
oligosaccharides (HMOs) in breastmilk are instrumental for the formation of a bifidobacteria …
Implications of the changing epidemiology of inflammatory bowel disease in a changing world
The epidemiology of inflammatory bowel disease (IBD) has undergone considerable shifts
since its emergence in the Western world over a century ago, especially in the last few …
since its emergence in the Western world over a century ago, especially in the last few …
[HTML][HTML] A distinct clade of Bifidobacterium longum in the gut of Bangladeshi children thrives during weaning
The gut microbiome has an important role in infant health and development. We
characterized the fecal microbiome and metabolome of 222 young children in Dhaka …
characterized the fecal microbiome and metabolome of 222 young children in Dhaka …
[HTML][HTML] The developing infant gut microbiome: a strain-level view
At birth, neonates provide a vast habitat awaiting microbial colonization. Microbiome
assembly is a complex process involving microbial seeding and succession driven by …
assembly is a complex process involving microbial seeding and succession driven by …