Recent advances in engineered materials for immunotherapy‐involved combination cancer therapy

JL Liang, GF Luo, WH Chen, XZ Zhang - Advanced Materials, 2021 - Wiley Online Library
Immunotherapy that can activate immunity or enhance the immunogenicity of tumors has
emerged as one of the most effective methods for cancer therapy. Nevertheless, single …

Advances and perspectives in carrier-free nanodrugs for cancer chemo-monotherapy and combination therapy

L Huang, S Zhao, F Fang, T Xu, M Lan, J Zhang - Biomaterials, 2021 - Elsevier
Nanocarrier-based drug delivery systems hold impressive promise for biomedical
application because of their excellent water dispersibility, prolonged blood circulation time …

Bioinspired nanotopographical design of drug delivery systems

JA Finbloom, C Huynh, X Huang… - Nature Reviews …, 2023 - nature.com
Effective drug delivery is important in the treatment of various biomedical conditions, ranging
from autoimmune disorders to cancer and bacterial infections. Nanostructured systems can …

[HTML][HTML] Green modified-UiO-66/MXene sandwich composites for gene-chemotherapy synergistic cancer suppression: Co-delivery of doxorubicin and pCRISPR

M Tavakolizadeh, M Atarod, SJS Tabaei… - Alexandria Engineering …, 2023 - Elsevier
Advancements in material science and engineering, especially in the field of porous
nanomaterials lead to new types of therapeutics and technologies. Among different types of …

Advances in nanoparticle development for improved therapeutics delivery: nanoscale topographical aspect

RK Singh, JC Knowles, HW Kim - Journal of tissue …, 2019 - journals.sagepub.com
Nanoparticle-based therapeutics delivery holds great promise for the treatment of intractable
diseases. The high loading of drug molecules and their precise delivery to target sites are …

Biomedical nanoparticle design: What we can learn from viruses

SM Figueroa, D Fleischmann, A Goepferich - Journal of Controlled Release, 2021 - Elsevier
Viruses are nanomaterials with a number of properties that surpass those of many synthetic
nanoparticles (NPs) for biomedical applications. They possess a rigorously ordered …

Polyethyleneimine (PEI) as a polymer-based co-delivery system for breast cancer therapy

AI Fahira, R Amalia, MI Barliana… - … Cancer: Targets and …, 2023 - Taylor & Francis
Cancer has become one of the leading causes of morbidity and mortality worldwide. This
disease is classified broadly by tissue, organ, and system; different cancer types and …

Virus-inspired nanosystems for drug delivery

Z Liao, L Tu, X Li, XJ Liang, S Huo - Nanoscale, 2021 - pubs.rsc.org
With over millions of years of evolution, viruses can infect cells efficiently by utilizing their
unique structures. Similarly, the drug delivery process is designed to imitate the viral …

[HTML][HTML] Development and optimization of paclitaxel loaded Eudragit/PLGA nanoparticles by simplex lattice mixture design: Exploration of improved hemocompatibility …

G Jeswani, L Chablani, U Gupta, RK Sahoo… - Biomedicine & …, 2021 - Elsevier
Anemia is the most common hematological abnormality of chemotherapy, which is
responsible for poor clinical outcomes. To overcome this complication, the present study …

Why synthetic virus-like nanoparticles can achieve higher cellular uptake efficiency?

J Li, J Wang, Q Yao, T Li, Y Yan, Z Li, J Zhang - Nanoscale, 2020 - pubs.rsc.org
Experimental studies in recent years have demonstrated that the cellular uptake properties
of nanoparticles can be improved by mimicking the spiky surfaces of viruses; however, little …