Myosteatosis in the context of skeletal muscle function deficit: an interdisciplinary workshop at the National Institute on Aging

R Correa-de-Araujo, O Addison, I Miljkovic… - Frontiers in …, 2020 - frontiersin.org
Skeletal muscle fat infiltration (known as myosteatosis) is an ectopic fat depot that increases
with aging and is recognized to negatively correlate with muscle mass, strength, and mobility …

Skeletal muscle inflammation and insulin resistance in obesity

H Wu, CM Ballantyne - The Journal of clinical investigation, 2017 - Am Soc Clin Investig
Obesity is associated with chronic inflammation, which contributes to insulin resistance and
type 2 diabetes mellitus. Under normal conditions, skeletal muscle is responsible for the …

Regulation of postabsorptive and postprandial glucose metabolism by insulin-dependent and insulin-independent mechanisms: an integrative approach

GD Dimitriadis, E Maratou, A Kountouri, M Board… - Nutrients, 2021 - mdpi.com
Glucose levels in blood must be constantly maintained within a tight physiological range to
sustain anabolism. Insulin regulates glucose homeostasis via its effects on glucose …

Stronger association of triglyceride glucose index than the HOMA-IR with arterial stiffness in patients with type 2 diabetes: a real-world single-centre study

S Wang, J Shi, Y Peng, Q Fang, Q Mu, W Gu… - Cardiovascular …, 2021 - Springer
Background The triglyceride-glucose index (TyG index) has been proposed as a simple and
reliable alternative insulin resistance (IR) marker, while the homeostasis model assessment …

Plasma concentrations of lipids during pregnancy and the risk of gestational diabetes mellitus: A longitudinal study: 妊娠期间的血脂浓度与妊娠糖尿病风险: 一项纵向 …

W Bao, S Dar, Y Zhu, J Wu, S Rawal, S Li… - Journal of …, 2018 - Wiley Online Library
摘要背景目前已经有研究证实血脂异常与妊娠糖尿病(gestational diabetes mellitus, GDM)
相关, 但是很少有研究对整个妊娠期间的血脂进行纵向测量. 当前这项研究的目的是描述整个 …

Aging is accompanied by a blunted muscle protein synthetic response to protein ingestion

BT Wall, SH Gorissen, B Pennings, R Koopman… - PloS one, 2015 - journals.plos.org
Purpose Progressive loss of skeletal muscle mass with aging (sarcopenia) forms a global
health concern. It has been suggested that an impaired capacity to increase muscle protein …

The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic clamp

F Guerrero-Romero, LE Simental-Mendía… - The Journal of …, 2010 - academic.oup.com
Context: To meet the worldwide challenge of emerging diabetes, accessible and
inexpensive tests to identify insulin resistance are needed. Objective: To evaluate the …

The need for standardized assessment of muscle quality in skeletal muscle function deficit and other aging-related muscle dysfunctions: a symposium report

R Correa-de-Araujo, MO Harris-Love, I Miljkovic… - Frontiers in …, 2017 - frontiersin.org
A growing body of scientific literature suggests that not only changes in skeletal muscle
mass, but also other factors underpinning muscle quality, play a role in the decline in …

The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance in apparently healthy subjects

LE Simental-Mendía, M Rodríguez-Morán… - … syndrome and related …, 2008 - liebertpub.com
Background: Because the insulin test is expensive and is not available in most laboratories
in the cities of undeveloped countries, we tested whether the product of fasting triglycerides …

Polycystic ovary syndrome

DA Ehrmann - New England Journal of Medicine, 2005 - Mass Medical Soc
The polycystic ovary syndrome is one of the most common hormonal disorders affecting
women. It has multiple components—reproductive, metabolic, and cardiovascular—with …