Abstract Procollagen-lysine, 2-oxoglutarate 5-dioxygenases (PLODs) are a set of enzymes
involved in the hydroxylation of lysine and stabilization of collagen by crosslinks. Previous …

Reactive oxygen species (ROS) metabolism is essential for the homeostasis of cells.
Appropriate production of ROS is an important signaling molecule, but excessive ROS …

Oxidative stress caused by an imbalance in the formation and removal of reactive oxygen
species (ROS) plays an important role in the development of several cardiovascular …

Research question Adenomyosis is a common uterine disorder of uncertain causes. Can
transcriptomic analyses of the endometrium and myometrium reveal potential mechanisms …

It is well‐documented that diabetes is an inflammatory and oxidative disease, with an
escalating global burden. Still, there is no definite treatment for diabetes or even prevention …

Over the last century, Western societies experienced a demographic shift driven by
increased lifespan and decreased fertility, resulting in the subversion of the world's …

Aims: Diabetes increases oxidative stress in the retina and dysfunctions their mitochondria,
accelerating capillary cell apoptosis. A 66 kDa adaptor protein, p66Shc, is considered as a …

Triple-negative breast cancer (TNBC) is highly aggressive and metastatic, and has the
poorest prognosis among all breast cancer subtypes. Activated β-catenin is enriched in …

Abstract FAT atypical cadherin 1 (FAT1) is among the most frequently mutated genes in
many types of cancer. Its highest mutation rate is found in head and neck squamous cell …

While Lck has been widely recognized to play a pivotal role in the initiation of the T cell
receptor (TCR) signaling pathway, an understanding of the precise regulation of Lck in T …