A wealth of evidence supports the role of tumor immunotherapy as a vital therapeutic option
in cancer. In recent decades, accumulated studies have revealed the anticancer activities of …

N-linked glycosylation is one of the most abundant posttranslational modifications of
membrane-bound proteins in eukaryotes and affects a number of biological activities …

The tumour microenvironment (TME) imposes a major obstacle to infiltrating T-lymphocytes
and suppresses their function. Several immune checkpoint proteins that interfere with …

Immunotherapy sheds new light to cancer treatment and is satisfied by cancer patients.
However, immunotoxicity, single‐source antibodies, and single‐targeting stratege are …

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causing the COVID-19
respiratory disease pandemic utilizes unique 2′-o-methyltransferase (2′-O-MTase) …

Cancer therapy through anticancer drugs and radiotherapy is associated with several side
effects as well as tumor resistance to therapy. The genotoxic effects of chemotherapy and …

As an important part of complementary and alternative medicine, traditional Chinese
medicine (TCM) has been applied to treat a host of diseases for centuries. Over the years …

Cancer immunotherapy is the new generation and widely accepted form of tumour
treatment. It is, however, associated with exclusive challenges which include organ-specific …

The immune checkpoint molecules programmed cell death receptor 1 (PD-1) and
programmed death ligand 1 (PD-L1) are one of the most promising targets for tumor …

Tumor resistance to therapy modalities is one of the major challenges to the eradication of
cancer cells and complete treatment. Tumor includes a wide range of cancer and non …