Low birth rates and increasing life expectancy experienced by developed societies have
placed an unprecedented pressure on governments and the health system to deal …

Frontotemporal dementias are a clinically, neuroanatomically, and pathologically diverse
group of diseases that collectively constitute an important cause of young-onset dementia …

Background: Neuronal-and circuit-level abnormalities of excitation and inhibition are shown
to be associated with tau and amyloid-beta (Aβ) in preclinical models of Alzheimer's disease …

The syndromes caused by frontotemporal lobar degeneration have highly heterogeneous
and overlapping clinical features. There has been great progress in the refinement of clinical …

Behavioural disinhibition is a common feature of the syndromes associated with
frontotemporal lobar degeneration (FTLD). It is associated with high morbidity and lacks …

Predicting biomedical outcomes from Magnetoencephalography and
Electroencephalography (M/EEG) is central to applications like decoding, brain-computer …

Neural oscillations and signal complexity have been widely studied in neurodegenerative
diseases, whereas aperiodic activity has not been explored yet in those disorders. Here, we …

Background Synaptic loss is a prominent and early feature of many neurodegenerative
diseases. Objectives We tested the hypothesis that synaptic density is reduced in the …

Abstract Purpose of Review The term primary progressive aphasia (PPA) refers to a diverse
group of dementias that present with prominent and early problems with speech and …

Neural synchrony is intricately balanced in the normal resting brain but becomes altered in
Alzheimer's disease (AD). To determine the neurophysiological manifestations associated …