[HTML][HTML] Type 2 immunity in asthma
M Caminati, DL Pham, D Bagnasco… - World Allergy …, 2018 - Springer
Type 2-immunity represents the typical adaptive response to allergen exposure in atopic
individuals. It mainly involves Th2 cells and immunoglobulin E, as the main orchestrators of …
individuals. It mainly involves Th2 cells and immunoglobulin E, as the main orchestrators of …
'Real‐life'effectiveness studies of omalizumab in adult patients with severe allergic asthma: systematic review
I Abraham, A Alhossan, CS Lee, H Kutbi… - Allergy, 2016 - Wiley Online Library
Abstract We reviewed 24 'real‐life'effectiveness studies of omalizumab in the treatment of
severe allergic asthma that included 4117 unique patients from 32 countries with significant …
severe allergic asthma that included 4117 unique patients from 32 countries with significant …
[HTML][HTML] Characterization of severe asthma worldwide: data from the International Severe Asthma Registry
E Wang, ME Wechsler, TN Tran, LG Heaney, RC Jones… - Chest, 2020 - Elsevier
Background Clinical characteristics of the international population with severe asthma are
unknown. Intercountry comparisons are hindered by variable data collection within regional …
unknown. Intercountry comparisons are hindered by variable data collection within regional …
The severe asthma network in Italy: findings and perspectives
Background Severe Asthma Network in Italy (SANI) is a registry of patients recruited by
accredited centers on severe asthma. Objective To analyze epidemiological, clinical …
accredited centers on severe asthma. Objective To analyze epidemiological, clinical …
[HTML][HTML] Real-world effectiveness of omalizumab in severe allergic asthma: a meta-analysis of observational studies
J Bousquet, M Humbert, PG Gibson, K Kostikas… - The Journal of Allergy …, 2021 - Elsevier
Background Assessment of clinical outcomes in the real-world corroborates findings from
randomized controlled trials (RCTs). Objective This meta-analysis evaluated real-world data …
randomized controlled trials (RCTs). Objective This meta-analysis evaluated real-world data …
[HTML][HTML] The eXpeRience registry: the 'real-world'effectiveness of omalizumab in allergic asthma
GJ Braunstahl, CW Chen, R Maykut, P Georgiou… - Respiratory …, 2013 - Elsevier
Omalizumab has demonstrated therapeutic benefits in controlled clinical trials. Evaluation of
outcomes in real-world clinical practice is needed to provide a complete understanding of …
outcomes in real-world clinical practice is needed to provide a complete understanding of …
“Real-life” effectiveness studies of omalizumab in adult patients with severe allergic asthma: meta-analysis
A Alhossan, CS Lee, K MacDonald… - The Journal of Allergy and …, 2017 - Elsevier
Background After the approval of omalizumab for severe allergic asthma, a total of 25
studies have evaluated the effectiveness of omalizumab under “real-life” conditions of …
studies have evaluated the effectiveness of omalizumab under “real-life” conditions of …
[HTML][HTML] An algorithmic approach for the treatment of severe uncontrolled asthma
E Zervas, K Samitas, AI Papaioannou… - ERJ open …, 2018 - Eur Respiratory Soc
A small subgroup of patients with asthma suffers from severe disease that is either partially
controlled or uncontrolled despite intensive, guideline-based treatment. These patients have …
controlled or uncontrolled despite intensive, guideline-based treatment. These patients have …
Systematic literature review of the clinical, humanistic, and economic burden associated with asthma uncontrolled by GINA Steps 4 or 5 treatment
S Chen, S Golam, J Myers, C Bly… - … medical research and …, 2018 - Taylor & Francis
Objective: This study sought to characterize the epidemiologic, clinical, humanistic, and
economic burden of patients with asthma uncontrolled by GINA Steps 4 or 5 treatment …
economic burden of patients with asthma uncontrolled by GINA Steps 4 or 5 treatment …
Short-and long-term real-world effectiveness of omalizumab in severe allergic asthma: systematic review of 42 studies published 2008-2018
Introduction: Omalizumab is a recombinant monoclonal anti-IgE antibody approved in the
US as add-on treatment in moderate-to-severe allergic asthma (in severe allergic asthma …
US as add-on treatment in moderate-to-severe allergic asthma (in severe allergic asthma …