Omalizumab management beyond clinical trials: the added value of a network model

M Caminati, G Senna, FC Bianchi, MR Marchi… - Pulmonary …, 2014 - Elsevier
Background Omalizumab is effective and safe in severe allergic asthma. Few data are
available about its impact on lung function and on asthma comorbidities, long-term follow-up …

The Portuguese Severe Asthma Registry: development, features, and data sharing policies

A Sá-Sousa, JA Fonseca, AM Pereira… - BioMed Research …, 2018 - Wiley Online Library
The Portuguese Severe Asthma Registry (Registo de Asma Grave Portugal, RAG) was
developed by an open collaborative network of asthma specialists. RAG collects data from …

[PDF][PDF] Severe asthma management in the era of biologics: insights of the Italian Registry on Severe Asthma (IRSA)

MB Bilò, L Antonicelli, M Carone, F De Michele… - Eur Ann Allergy Clin …, 2021 - aaiito.it
Summary Background. Il Registro italiano dell'Asma Severa (IRSA) è il più recente e più
vasto registro in Italia. Obbiettivo. Migliorare la conoscenza sulle caratteristiche cliniche e …

'Real-world'effectiveness of omalizumab in adults with severe allergic asthma: a meta-analysis

KM Faulkner, K MacDonald, I Abraham… - Expert Review of …, 2021 - Taylor & Francis
ABSTRACT Background: Severe asthma affects 5–10% of the 350 million people with
asthma worldwide. Findings from the authors' previous meta-analysis supported …

[HTML][HTML] Documento de consenso de asma grave en adultos. Actualización 2022

FJ Alvarez-Gutiérrez, M Blanco-Aparicio… - Open Respiratory …, 2022 - Elsevier
Severe asthma is a heterogeneous syndrome with several clinical variants and often
represents a complex disease requiring a specialized and multidisciplinary approach, as …

Asthma control and exacerbations in patients with severe asthma treated with omalizumab in Portugal

AS Sousa, AM Pereira, JA Fonseca, LF Azevedo… - Revista Portuguesa de …, 2015 - Elsevier
The analysis of outcomes from patients with severe asthma treated with omalizumab, using
real-life prospective data, should contribute to future informed decisions about this treatment …

Novel biological therapies in severe asthma: targeting the right trait

G Varricchi, G Marone, G Spadaro… - Current medicinal …, 2019 - ingentaconnect.com
Asthma is a heterogeneous disease characterized by chronic airway inflammation that
results in a wide spectrum of clinical manifestations. Patients with severe asthma represent a …

[HTML][HTML] Prevalence of perennial severe allergic asthma in Italy and effectiveness of omalizumab in its management: PROXIMA–an observational, 2 phase, patient …

GW Canonica, M Bartezaghi, R Marino… - Clinical and Molecular …, 2015 - Springer
Background We designed the PROXIMA study (Patient-Reported Outcomes and Xolair® In
the Management of Asthma) to determine the proportion of patients with severe asthma …

[HTML][HTML] Long-term effectiveness and safety of omalizumab in pediatric and adult patients with moderate-to-severe inadequately controlled allergic asthma

NA Hanania, R Niven, P Chanez, D Antoine… - World Allergy …, 2022 - Elsevier
Omalizumab is recommended as an add-on therapy in patients aged≥ 6 years with
inadequately controlled, moderate-to-severe persistent allergic asthma. The efficacy and …

[HTML][HTML] Effectiveness and pharmacoeconomic analysis of the treatment of severe asthma with omalizumab in clinical practice

E Martínez-Moragón, M Climent, E Chiner… - Farmacia …, 2019 - Elsevier
Objective To assess socio-sanitary expenditure after the addition of omalizumab to standard
treatment in the control of severe asthma and to analyse its effectiveness under standard …