Role of microRNAs, circRNAs and long noncoding RNAs in acute myeloid leukemia
Acute myeloid leukemia (AML) is a malignant tumor of the immature myeloid hematopoietic
cells in the bone marrow (BM). It is a highly heterogeneous disease, with rising morbidity …
cells in the bone marrow (BM). It is a highly heterogeneous disease, with rising morbidity …
Clinical significance of microRNAs in hematologic malignancies and hematopoietic stem cell transplantation
A Sevcikova, I Fridrichova, N Nikolaieva, L Kalinkova… - Cancers, 2023 - mdpi.com
Simple Summary Dysregulated microRNA (miRNA) expression has been described in the
initiation and progression of a wide spectrum of hematologic malignancies. Moreover …
initiation and progression of a wide spectrum of hematologic malignancies. Moreover …
Myeloid-derived suppressor cells shift Th17/Treg ratio and promote systemic lupus erythematosus progression through arginase-1/miR-322-5p/TGF-β pathway
B Pang, Y Zhen, C Hu, Z Ma, S Lin, H Yi - Clinical Science, 2020 - portlandpress.com
Immune cells play important roles in systemic lupus erythematosus (SLE). We previously
found that myeloid-derived suppressor cell (MDSC)-derived arginase-1 (Arg-1) promoted …
found that myeloid-derived suppressor cell (MDSC)-derived arginase-1 (Arg-1) promoted …
Polyamines from myeloid-derived suppressor cells promote Th17 polarization and disease progression
C Hu, Y Zhen, Z Ma, L Zhao, H Wu, C Shu, B Pang… - Molecular Therapy, 2023 - cell.com
Myeloid-derived suppressor cells (MDSCs) are a group of immature myeloid cells that play
an important role in diseases. MDSCs promote Th17 differentiation and aggravate systemic …
an important role in diseases. MDSCs promote Th17 differentiation and aggravate systemic …
[HTML][HTML] A novel six-microRNA-based model to improve prognosis prediction of breast cancer
J Lai, H Wang, Z Pan, F Su - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
Current tumor-node-metastasis (TNM) stage is unable to accurately predict the overall
survival (OS) in breast cancer (BC) patients. This study aimed to construct a microRNA …
survival (OS) in breast cancer (BC) patients. This study aimed to construct a microRNA …
High serum extracellular vesicle miR-10b expression predicts poor prognosis in patients with acute myeloid leukemia
Z Fang, X Wang, J Wu, R Xiao, J Liu - Cancer Biomarkers, 2020 - content.iospress.com
BACKGROUND: Increasing evidence have demonstrated that serum extracellular vesicle
microRNAs (EV-miRNAs) are promising noninvasive biomarkers for various cancer types …
microRNAs (EV-miRNAs) are promising noninvasive biomarkers for various cancer types …
MicroRNA profiling of paediatric AML with FLT-ITD or MLL-rearrangements: Expression signatures and in vitro modulation of miR-221-3p and miR-222-3p with …
PP Leoncini, P Vitullo, S Reddel… - Oncology …, 2022 - spandidos-publications.com
Novel therapeutic strategies are needed for paediatric patients affected by Acute Myeloid
Leukaemia (AML), particularly for those at high-risk for relapse. MicroRNAs (miRs) have …
Leukaemia (AML), particularly for those at high-risk for relapse. MicroRNAs (miRs) have …
Implication of microRNAs in carcinogenesis with emphasis on hematological malignancies and clinical translation
Z Gaál - International Journal of Molecular Sciences, 2022 - mdpi.com
MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNAs, that are
involved in the multistep process of carcinogenesis, contributing to all established hallmarks …
involved in the multistep process of carcinogenesis, contributing to all established hallmarks …
MiRNA expression as outcome predictor in pediatric AML: systematic evaluation of a new model
I Ellson, J Martorell-Marugán, P Carmona-Sáez… - NPJ Genomic …, 2024 - nature.com
Accurately predicting patient outcomes is essential for optimizing treatment and improving
outcomes in pediatric acute myeloid leukemia (AML). In recent years, microRNAs have …
outcomes in pediatric acute myeloid leukemia (AML). In recent years, microRNAs have …
The promising role of non-coding RNAs as biomarkers and therapeutic targets for leukemia
MH Ghazimoradi, N Karimpour-Fard, S Babashah - Genes, 2023 - mdpi.com
Early-stage leukemia identification is crucial for effective disease management and leads to
an improvement in the survival of leukemia patients. Approaches based on cutting-edge …
an improvement in the survival of leukemia patients. Approaches based on cutting-edge …