The impact of reducing dose frequency on health outcomes

A Richter, SE Anton, P Koch, SL Dennett - Clinical therapeutics, 2003 - Elsevier
Background: Dosing schedules may be one important factor determining whether patients
take their prescribed medication. Schedules may influence whether a patient stays on the …

Optimizing the management of postmenopausal osteoporosis with bisphosphonates: the emerging role of intermittent therapy

PD Miller - Clinical therapeutics, 2005 - Elsevier
BACKGROUND:: The utility of bisphosphonates in the treatment of postmenopausal
osteoporosis is compromised by the requirement of frequent oral administration or complex …

[HTML][HTML] The effect of vortioxetine on health-related quality of life in patients with major depressive disorder

I Florea, N Danchenko, M Brignone, H Loft, B Rive… - Clinical …, 2015 - Elsevier
Purpose Major depressive disorder (MDD) has detrimental effects on health-related quality
of life (HRQoL). We describe the effect of vortioxetine on HRQoL in MDD patients by using …

Switching to duloxetine from selective serotonin reuptake inhibitor antidepressants: a multicenter trial comparing 2 switching techniques.

DGS Perahia, D Quail, D Desaiah… - Journal of Clinical …, 2008 - psychiatrist.com
Objective: To compare 2 methods of switching selective serotonin reuptake inhibitor (SSRI)
nonresponders or partial responders to duloxetine. Method: Adult outpatients with DSM-IV …

[图书][B] Depression: Treatment strategies and management

TL Schwartz, TJ Petersen - 2006 - books.google.com
Guiding clinicians toward the most effective treatment regimens, this reference offers
detailed coverage of the symptomatology, diagnosis, epidemiology, and etiology of …

Immediate switching of antidepressant therapy: results from a clinical trial of duloxetine

MM Wohlreich, CH Mallinckrodt, JG Watkin… - Annals of Clinical …, 2005 - Taylor & Francis
Background. Approximately half of all treated depressed patients fail to show adequate
response to their initially prescribed antidepressant medication. Switching to another …

Ibandronate: the evolution of a once-a-month oral therapy for postmenopausal osteoporosis

DW Dempster, MA Bolognese - Journal of Clinical Densitometry, 2006 - Elsevier
Bisphosphonates have been shown to be highly effective in preventing and treating
postmenopausal osteoporosis (PMO) and the associated risk of fracture. However, poor …

An open-label study of duloxetine for the treatment of major depressive disorder: comparison of switching versus initiating treatment approaches

MM Wohlreich, JM Martinez… - Journal of clinical …, 2005 - journals.lww.com
This study compared the stabilized duloxetine dose through approximately 12 weeks of
treatment in patients initiating duloxetine therapy with that in patients switching to duloxetine …

Difficult-to-treat depressions: a primary care perspective

JS Manning - Journal of Clinical Psychiatry, 2003 - psychiatrist.com
Depression is common in primary care and more difficult to treat than many clinicians are
aware. The goal of treatment is symptomatic remission, and by current estimates 50% or …

氟西汀肠溶片与氟西汀片对抑郁症巩固期患者疗效的双盲对照研究

张鸿燕, 姜荣环, 舒良, 李华芳, 殷美莉, 顾牛范… - 中华精神科杂志, 2007 - cqvip.com
目的评价氟西汀肠溶片对抑郁症缓解期患者的疗效及安全性. 方法采用随机, 双盲, 活性药对照,
多中心临床研究方法. 按1: 1 将232 例受试者随机分配到氟西汀肠溶片组(116 例) …