[HTML][HTML] Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research

X Tong, R Tang, M Xiao, J Xu, W Wang… - Journal of hematology & …, 2022 - Springer
Many types of human cells self-destruct to maintain biological homeostasis and defend the
body against pathogenic substances. This process, called regulated cell death (RCD), is …

[HTML][HTML] Regulatory roles of copper metabolism and cuproptosis in human cancers

Z Wang, D Jin, S Zhou, N Dong, Y Ji, P An… - Frontiers in …, 2023 - frontiersin.org
Copper is an essential micronutrient for human body and plays a vital role in various
biological processes including cellular respiration and free radical detoxification. Generally …

[HTML][HTML] System analysis based on the cuproptosis-related genes identifies LIPT1 as a novel therapy target for liver hepatocellular carcinoma

C Yan, Y Niu, L Ma, L Tian, J Ma - Journal of Translational Medicine, 2022 - Springer
Background Liver hepatocellular carcinoma (LIHC) ranks sixth among the most common
types of cancer with a high mortality rate. Cuproptosis is a newly discovered type of cell …

[HTML][HTML] Different types of cell death in diabetic endothelial dysfunction

J Shen, W San, Y Zheng, S Zhang, D Cao… - Biomedicine & …, 2023 - Elsevier
Diabetes mellitus is a metabolic disease caused by disorders of insulin secretion and
utilization. Long-term hyperglycemia, insulin resistance, and disorders of glucose and lipid …

[HTML][HTML] Identification of cuproptosis-related subtypes, characterization of tumor microenvironment infiltration, and development of a prognosis model in breast cancer

Z Li, H Zhang, X Wang, Q Wang, J Xue, Y Shi… - Frontiers in …, 2022 - frontiersin.org
Breast cancer (BC) is now the most frequent and lethal cancer among women. Cuproptosis
is a newly identified programmed cell death process that has been connected to tumor …

Copper homeostasis and cuproptosis in cancer immunity and therapy

WQ Liu, WR Lin, L Yan, WH Xu… - Immunological Reviews, 2024 - Wiley Online Library
Copper is an essential nutrient for maintaining enzyme activity and transcription factor
function. Excess copper results in the aggregation of lipoylated dihydrolipoamide S …

[HTML][HTML] A novel cuproptosis-related lncRNA signature predicts the prognosis and immune landscape in bladder cancer

Y Bai, Q Zhang, F Liu, J Quan - Frontiers in Immunology, 2022 - frontiersin.org
Background Bladder cancer (BLCA) is one of the deadliest diseases, with over 550,000 new
cases and 170,000 deaths globally every year. Cuproptosis is a copper-triggered …

[HTML][HTML] Copper homeostasis and cuproptosis in tumor pathogenesis and therapeutic strategies

C Bian, Z Zheng, J Su, S Chang, H Yu, J Bao… - Frontiers in …, 2023 - frontiersin.org
Copper is an indispensable micronutrient for the development and replication of all
eukaryotes, and its redox properties are both harmful and beneficial to cells. An imbalance …

Cuproptosis and cuproptosis-related genes: Emerging potential therapeutic targets in breast cancer

X Liu, B Luo, X Wu, Z Tang - Biochimica et Biophysica Acta (BBA)-Reviews …, 2023 - Elsevier
Breast cancer is one of the most common malignant tumors in women worldwide, and thus, it
is important to enhance its treatment efficacy [1]. Copper has emerged as a critical trace …

[HTML][HTML] A bibliometric analysis of ferroptosis, necroptosis, pyroptosis, and cuproptosis in cancer from 2012 to 2022

YD Miao, W Quan, X Dong, J Gan, CF Ji, JT Wang… - Cell death …, 2023 - nature.com
This study aims to visualize research hotspots and trends of “ferroptosis in
cancer”,“necroptosis in cancer”,“pyroptosis in cancer”, and “cuproptosis in cancer” through a …