Spatially resolved immune exhaustion within the alloreactive microenvironment predicts liver transplant rejection

A Barbetta, B Rocque, S Bangerth, K Street… - Science …, 2024 - science.org
Allograft rejection is common following clinical organ transplantation, but defining specific
immune subsets mediating alloimmunity has been elusive. Calcineurin inhibitor dose …

[HTML][HTML] Intragraft regulatory T cells in the modern era: what can high-dimensional methods tell us about pathways to allograft acceptance?

KF Bei, S Moshkelgosha, BJ Liu, S Juvet - Frontiers in Immunology, 2023 - frontiersin.org
Replacement of diseased organs with transplanted healthy donor ones remains the best
and often only treatment option for end-stage organ disease. Immunosuppressants have …

[HTML][HTML] Single-Cell RNA Sequencing in Organ and Cell Transplantation

R Abedini-Nassab, F Taheri, A Emamgholizadeh… - Biosensors, 2024 - mdpi.com
Single-cell RNA sequencing is a high-throughput novel method that provides transcriptional
profiling of individual cells within biological samples. This method typically uses …

[HTML][HTML] Harnessing the n+ 1 dimensions of single-cell omics data for the prediction and prevention of human diseases

D Gaudilliere, B Gaudilliere - Seminars in immunopathology, 2023 - Springer
Harnessing the n+1 dimensions of single-cell omics data for the prediction and prevention of
human diseases | Seminars in Immunopathology Skip to main content SpringerLink Account …