Recent innovations in bacterial infection detection and treatment

C Deusenbery, Y Wang, A Shukla - ACS Infectious Diseases, 2021 - ACS Publications
Bacterial infections are a major threat to human health, exacerbated by increasing antibiotic
resistance. These infections can result in tremendous morbidity and mortality, emphasizing …

Hierarchical materials from high information content macromolecular building blocks: construction, dynamic interventions, and prediction

L Shao, J Ma, JL Prelesnik, Y Zhou, M Nguyen… - Chemical …, 2022 - ACS Publications
Hierarchical materials that exhibit order over multiple length scales are ubiquitous in nature.
Because hierarchy gives rise to unique properties and functions, many have sought …

The overview of antimicrobial peptide‐coated implants against oral bacterial infections

Z Sun, L Ma, X Sun, AJ Sloan… - …, 2023 - Wiley Online Library
Dental implants are the most common therapeutic approach for resolving tooth loss and
damage. Despite technical advances in treatment, implant failure rates can be as high as …

Design, synthesis, and biological evaluation of membrane-active bakuchiol derivatives as effective broad-spectrum antibacterial agents

H Li, J Liu, CF Liu, H Li, J Luo, S Fang… - Journal of Medicinal …, 2021 - ACS Publications
Infections caused by drug-resistant bacteria seriously endanger human health and global
public health. Therefore, it is urgent to discover and develop novel antimicrobial agents to …

Antimicrobial peptide mimics for clinical use: does size matter?

J Svenson, N Molchanova, CI Schroeder - Frontiers in Immunology, 2022 - frontiersin.org
The search for efficient antimicrobial therapies that can alleviate suffering caused by
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …

Rational Design of Phe‐BODIPY Amino Acids as Fluorogenic Building Blocks for Peptide‐Based Detection of Urinary Tract Candida Infections

L Mendive‐Tapia, D Mendive‐Tapia… - Angewandte Chemie …, 2022 - Wiley Online Library
Fungal infections caused by Candida species are among the most prevalent in hospitalized
patients. However, current methods for the detection of Candida fungal cells in clinical …

Antibacterial copolypeptoids with potent activity against drug resistant bacteria and biofilms, excellent stability, and recycling property

B Zhang, M Zhang, M Lin, X Dong, X Ma, Y Xu, J Sun - Small, 2022 - Wiley Online Library
The preparation of a type of innovative cationic copolypeptoid antimicrobials containing
various hydrophobic moieties that resemble both structure and membrane‐lytic antibacterial …

Antimicrobial Peptide–Peptoid Hybrids with and without Membrane Disruption

E Bonvin, H Personne, T Paschoud… - ACS infectious …, 2023 - ACS Publications
Among synthetic analogues of antimicrobial peptides (AMPs) under investigation to address
antimicrobial resistance, peptoids (N-alkylated oligoglycines) have been reported to act both …

Host defense peptide-mimicking polymers and polymeric-brush-tethered host defense peptides: recent developments, limitations, and potential success

H Etayash, REW Hancock - Pharmaceutics, 2021 - mdpi.com
Amphiphilic antimicrobial polymers have attracted considerable interest as structural mimics
of host defense peptides (HDPs) that provide a broad spectrum of activity and do not induce …

Photothermal nanoagent for anti-inflammation through macrophage repolarization following antibacterial therapy

Y Xu, Y Cai, Y Xia, Q Wu, M Li, N Guo, Y Tu… - European Polymer …, 2023 - Elsevier
Owing to the ignorable bacterial resistance, photothermal therapy (PTT) has been widely
studied for bacterial infection. However, few research efforts have focused primarily on the …