The gastrointestinal tract is the only internal organ to have evolved with its own independent
nervous system, known as the enteric nervous system (ENS). This Review provides an …

One of the most transformative developments in neurogastroenterology is the realization that
many functions normally attributed to enteric neurons involve interactions with enteric glial …

Irritable bowel syndrome (IBS) is the most prevalent disorder of brain-gut interactions that
affects between 5 and 10% of the general population worldwide. The current symptom …

The enteric nervous system (ENS) is the largest division of the peripheral nervous system
and closely resembles components and functions of the central nervous system. Although …

The enteric nervous system (ENS) is large, complex and uniquely able to orchestrate
gastrointestinal behaviour independently of the central nervous system (CNS). An intact …

The nervous system—in particular, the brain and its cognitive abilities—is among humans'
most distinctive and impressive attributes. How the nervous system has changed in the …

Galectin-3 (Gal-3) regulates basic cellular functions such as cell–cell and cell–matrix
interactions, growth, proliferation, differentiation, and inflammation. It is not surprising …

The enteric nervous system (ENS) is an extensive network comprising millions of neurons
and glial cells contained within the wall of the gastrointestinal tract. The major functions of …

Background Intraneuronal α-synuclein (α-Syn) aggregates known as Lewy bodies (LBs) and
the loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) are the …

The digestive system is innervated through its connections with the central nervous system
(CNS) and by the enteric nervous system (ENS) within the wall of the gastrointestinal tract …