Dysregulated biological behaviors of trophoblast cells can result in recurrent spontaneous
abortion (RSA)—whose underlying etiology still remains insufficient. Autophagy, a …

Efficient epigenetic reprogramming is crucial for the in vitro development of mammalian
somatic cell nuclear transfer (SCNT) embryos. The aberrant levels of histone H3 lysine 9 …

Although somatic cell nuclear transfer (SCNT) can be used to create transgenic pigs for
human xenotransplantation, low efficiency limits its use. Trichostatin A (TSA) promotes …

In this study, we analyzed the effects of the cloned embryo aggregation on in vitro embryo
development and embryo quality by measuring blastocyst diameter and cell number, DNA …

The oocyte growth and development in follicular environment are substantially accompanied
by surrounding somatic cumulus (CCs) and granulosa cells (GCs). During these processes …

This study aimed to evaluate the effect of meiotic arrest using phosphodiesterase type 3A
(PDE 3A) inhibitors, cilostamide and C-type natriuretic peptide (NPPC), on pre-maturation …

Lipid-rich bovine serum albumin (LR-BSA) has been reported to increase the survival rate of
blastocysts after freezing and thawing. However studies on the early development of in vitro …

M344 is a novel histone deacetylase inhibitor. There is no report on the effect of M344
treatment on the development of pig embryos after somatic cell nuclear transfer (SCNT). In …

Somatic cell nuclear transfer is a technique to create an embryo using an enucleated oocyte
and a donor nucleus. Nucleus of somatic cells must be reprogrammed in order to participate …

Objective: To evaluate the effect of treatment with trichostatin-A (TSA) on the production of
bovine embryos, expressing the gene of the green fluorescent protein (GFP) generated by …