Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination, and diagnostics

CE Demeure, O Dussurget, G Mas Fiol… - Genes & …, 2019 - nature.com
Plague is a vector-borne disease caused by Yersinia pestis. Transmitted by fleas from
rodent reservoirs, Y. pestis emerged< 6000 years ago from an enteric bacterial ancestor …

Peptidoglycan-associated lipoprotein (Pal) of Gram-negative bacteria: function, structure, role in pathogenesis and potential application in immunoprophylaxis

R Godlewska, K Wiśniewska, Z Pietras… - FEMS microbiology …, 2009 - academic.oup.com
The protein Pal (peptidoglycan-associated lipoprotein) is anchored in the outer membrane
(OM) of Gram-negative bacteria and interacts with Tol proteins. Tol–Pal proteins form two …

Lpp, the Braun lipoprotein, turns 50—major achievements and remaining issues

AT Asmar, JF Collet - FEMS microbiology letters, 2018 - academic.oup.com
The discovery of Escherichia coli Lpp as the first protein with three acyl groups covalently
attached to its N-terminal cysteine residue defined a new class of bacterial proteins, the …

Plague into the 21st century

T Butler - Clinical Infectious Diseases, 2009 - academic.oup.com
As an ancient scourge, plague caused deadly epidemics in medieval Europe, and in the
20th century, it caused extensive mortality in India and Vietnam. Crossing into the 21st …

Identifying virulence determinants of multidrug-resistant Klebsiella pneumoniae in Galleria mellonella

S Bruchmann, T Feltwell, J Parkhill… - Pathogens and …, 2021 - academic.oup.com
Infections caused by Klebsiella pneumoniae are a major public health threat. Extensively
drug-resistant and even pan-resistant strains have been reported. Understanding K …

Surface-Expressed Enolase Contributes to the Pathogenesis of Clinical Isolate SSU of Aeromonas hydrophila

J Sha, TE Erova, RA Alyea, S Wang… - Journal of …, 2009 - Am Soc Microbiol
In this study, we demonstrated that the surface-expressed enolase from diarrheal isolate
SSU of Aeromonas hydrophila bound to human plasminogen and facilitated the latter's …

Immune defense against pneumonic plague

ST Smiley - Immunological reviews, 2008 - Wiley Online Library
Yersinia pestis is one of the world's most virulent human pathogens. Inhalation of this Gram‐
negative bacterium causes pneumonic plague, a rapidly progressing and usually fatal …

The NlpD Lipoprotein Is a Novel Yersinia pestis Virulence Factor Essential for the Development of Plague

A Tidhar, Y Flashner, S Cohen, Y Levi, A Zauberman… - PloS one, 2009 - journals.plos.org
Yersinia pestis is the causative agent of plague. Previously we have isolated an attenuated
Y. pestis transposon insertion mutant in which the pcm gene was disrupted. In the present …

[HTML][HTML] Plague vaccine development: current research and future trends

SK Verma, U Tuteja - Frontiers in immunology, 2016 - frontiersin.org
Plague is one of the world's most lethal human diseases caused by Yersinia pestis, a Gram-
negative bacterium. Despite overwhelming studies for many years worldwide, there is no …

Molecular Darwinian Evolution of Virulence in Yersinia pestis

D Zhou, R Yang - Infection and immunity, 2009 - Am Soc Microbiol
The genus Yersinia consists of 15 species (www. bacterio. cict. fr/xz/yersinia. html), and only
three of them, Y. pestis, Y. pseudotuberculosis, and Y. enterocolitica, are pathogenic to …