The role of dopamine in NLRP3 inflammasome inhibition: Implications for neurodegenerative diseases
Abstract In the Central Nervous System (CNS), neuroinflammation orchestrated by microglia
and astrocytes is an innate immune response to counteract stressful and dangerous insults …
and astrocytes is an innate immune response to counteract stressful and dangerous insults …
[HTML][HTML] Photobiomodulation in Alzheimer's disease—A complementary method to state-of-the-art pharmaceutical formulations and nanomedicine?
Alzheimer's disease (AD), as a neurodegenerative disorder, usually develops slowly but
gradually worsens. It accounts for approximately 70% of dementia cases worldwide, and is …
gradually worsens. It accounts for approximately 70% of dementia cases worldwide, and is …
Upregulation of Ca2+-binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer's disease in Tg2576 mice
L La Barbera, A Nobili, E Cauzzi, I Paoletti… - Molecular …, 2022 - Springer
Background Recent clinical and experimental studies have highlighted the involvement of
Ventral Tegmental Area (VTA) dopamine (DA) neurons for the early pathogenesis of …
Ventral Tegmental Area (VTA) dopamine (DA) neurons for the early pathogenesis of …
Cell membrane-based nanomaterials for therapeutics of neurodegenerative diseases
Central nervous system (CNS) diseases such as Alzheimer's disease (AD), Parkinson's
disease (PD), glioblastoma (GBM), and peripheral nerve injury have been documented as …
disease (PD), glioblastoma (GBM), and peripheral nerve injury have been documented as …
Role of Exosomes in the Pathogenesis and Theranostic of Alzheimer's Disease and Parkinson's Disease
A He, M Wang, X Li, H Chen, K Lim, L Lu… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common
neurodegenerative diseases (NDDs) threatening the lives of millions of people worldwide …
neurodegenerative diseases (NDDs) threatening the lives of millions of people worldwide …
Drug discovery and development targeting dementia
Dementia, most often associated with neurodegenerative diseases, affects millions of
people worldwide, predominantly the elderly. Unfortunately, no treatment is still available …
people worldwide, predominantly the elderly. Unfortunately, no treatment is still available …
Intranasal Drug Delivery by Nanotechnology: Advances in and Challenges for Alzheimer's Disease Management
Alzheimer's disease, a progressive neurodegenerative condition, is characterized by a
gradual decline in cognitive functions. Current treatment approaches primarily involve the …
gradual decline in cognitive functions. Current treatment approaches primarily involve the …
Borneol-Modified Schisandrin B Micelles Cross the Blood–Brain Barrier To Treat Alzheimer's Disease in Aged Mice
F Li, Y Yu, Y Du, L Kong, Y Liu, J Wang… - ACS Chemical …, 2024 - ACS Publications
Objective: Schisandrin B (Sch B) is a bioactive dibenzocyclooctadiene derizative that is
prevalent in the fruit of Schisandra chinensis. Numerous studies have demonstrated that Sch …
prevalent in the fruit of Schisandra chinensis. Numerous studies have demonstrated that Sch …
Innovative Approaches to Alzheimer's Therapy: Harnessing the Power of Heterocycles, Oxidative Stress Management, and Nanomaterial Drug Delivery System
M Umar, Y Rehman, S Ambreen, SM Mumtaz… - Ageing Research …, 2024 - Elsevier
Alzheimer's disease (AD) presents a complex pathology involving amyloidogenic
proteolysis, neuroinflammation, mitochondrial dysfunction, and cholinergic deficits. Oxidative …
proteolysis, neuroinflammation, mitochondrial dysfunction, and cholinergic deficits. Oxidative …
Neuromodulation by nanozymes and ultrasound during Alzheimer's disease management
Alzheimer's disease (AD) is a neurodegenerative disorder with complex pathogenesis and
effective clinical treatment strategies for this disease remain elusive. Interestingly …
effective clinical treatment strategies for this disease remain elusive. Interestingly …