Second-hand smoke and human lung cancer
A Besaratinia, GP Pfeifer - The lancet oncology, 2008 - thelancet.com
Since the early 1980s, there has been growing concern about potential health
consequences of exposure to second-hand smoke (SHS). Despite SHS being established …
consequences of exposure to second-hand smoke (SHS). Despite SHS being established …
Mutational spectra of human cancer
GP Pfeifer, A Besaratinia - Human genetics, 2009 - Springer
The purpose of this review is to summarize the evidence that can be used to reconstruct the
etiology of human cancers from mutations found in tumors. Mutational spectra of the tumor …
etiology of human cancers from mutations found in tumors. Mutational spectra of the tumor …
Concordance of hydrogen peroxide–induced 8-oxo-guanine patterns with two cancer mutation signatures of upper GI tract tumors
Oxidative DNA damage has been linked to inflammation, cancer, and aging. Here, we have
mapped two types of oxidative DNA damage, oxidized guanines produced by hydrogen …
mapped two types of oxidative DNA damage, oxidized guanines produced by hydrogen …
[HTML][HTML] A narrative review of the role of diet and lifestyle factors in the development and prevention of endometrial cancer
HK Yasin, AH Taylor, T Ayakannu - Cancers, 2021 - mdpi.com
Simple Summary The incidence and prevalence of endometrial cancer is increasing
globally. The main factors involved in this increase have been the way women live today …
globally. The main factors involved in this increase have been the way women live today …
[HTML][HTML] Focus: skin: cutaneous photoprotection: a review of the current status and evolving strategies
Ultraviolet radiation (UVR) exposure is well established as the major environmental risk
factor for the development of melanoma, cutaneous squamous cell carcinoma (cSCC), and …
factor for the development of melanoma, cutaneous squamous cell carcinoma (cSCC), and …
Genetic and epigenetic alterations in normal tissues have differential impacts on cancer risk among tissues
S Yamashita, T Kishino, T Takahashi… - Proceedings of the …, 2018 - National Acad Sciences
Genetic and epigenetic alterations are both involved in carcinogenesis, and their low-level
accumulation in normal tissues constitutes cancer risk. However, their relative importance …
accumulation in normal tissues constitutes cancer risk. However, their relative importance …
[HTML][HTML] Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention
Exposure to environmental mutagens is an important cause of human cancer, and measures
to reduce mutagenic and carcinogenic exposures have been highly successful at controlling …
to reduce mutagenic and carcinogenic exposures have been highly successful at controlling …
[HTML][HTML] TP53 mutation characteristics in therapy-related myelodysplastic syndromes and acute myeloid leukemia is similar to de novo diseases
Background TP53 mutation is more prevalent in therapy-related myeloid neoplasms (t-MN)
than their de novo counterparts; however, the pattern of mutations involving TP53 gene in t …
than their de novo counterparts; however, the pattern of mutations involving TP53 gene in t …
Urinary levels of tobacco-specific nitrosamine metabolites in relation to lung cancer development in two prospective cohorts of cigarette smokers
(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and its glucuronides (sum of which is
denoted as total NNAL) are metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone …
denoted as total NNAL) are metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone …
Benzo (a) pyrene induced lung cancer: Role of dietary phytochemicals in chemoprevention
Lung cancer is the major cause of overall cancer deaths, and chemoprevention is a
promising strategy to control this disease. Benzo (a) pyrene [B (a) P], a polycyclic aromatic …
promising strategy to control this disease. Benzo (a) pyrene [B (a) P], a polycyclic aromatic …