The human body generates 10–100 billion cells every day, and the same number of cells
die to maintain homeostasis in our body. Cells infected by bacteria or viruses also die. The …

Annexins are cytosolic proteins with conserved three-dimensional structures that bind acidic
phospholipids in cellular membranes at elevated Ca2+ levels. Through this they act as Ca2+ …

Purpose: Glioblastoma represents the most common primary brain tumor. Although
antiangiogenics are used in the recurrent setting, they do not prolong survival. Glioblastoma …

Abstract Annexin A2 (ANXA2) is widely used as a marker in a variety of tumors. By
regulating multiple signal pathways, ANXA2 promotes the epithelial‐mesenchymal …

Annexin‐A1 has a well‐defined anti‐inflammatory role in the innate immune system, but its
function in adaptive immunity remains controversial. This glucocorticoid‐induced protein has …

The vertebrate annexin superfamily (AnxA) consists of 12 members of a calcium (Ca2+) and
phospholipid binding protein family which share a high structural homology. In keeping with …

The utricle of the inner ear, a vestibular sensory structure that mediates perception of linear
acceleration, is comprised of two morphologically and physiologically distinct types of …

Routine manipulation of the mouse genome has become a landmark in biomedical
research. Traits that are only associated with advanced developmental stages can now be …

Group 2 innate lymphoid cells (ILC2s) produce large amounts of type 2 cytokines including
interleukin-5 (IL-5) and IL-13 in response to various stimuli, causing allergic and …

Nasopharyngeal carcinoma (NPC) is a head and neck cancer with poor clinical outcomes
and insufficient treatments in Southeast Asian populations. Although concurrent …