Mesenchymal stem cells (MSCs), the most well-studied cell type in the field of stem cell
therapy, have multi-lineage differentiation and self-renewal potential. MSC-based therapies …

Autotaxin (ATX), also known as ENPP2, is the key enzyme in lysophosphatidic acid (LPA)
production. LPA acts on its receptors on the cell membrane to promote cell proliferation and …

The transcriptomic analysis of microarray and RNA-Seq datasets followed our own
bioinformatic pipeline to identify a transcriptional regulatory network of lung cancer. Twenty …

Strict control of iron homeostasis is critical for the maintenance of normal lung function. Iron
accumulates in the lungs of patients with idiopathic pulmonary fibrosis (PF), but the …

Malignant melanoma is the most aggressive and deadly skin cancer with an increasing
incidence worldwide whereas SCC is the second most common non-melanoma human skin …

Background Chronic obstructive pulmonary disease (COPD) is characterized by irreversible
lung tissue damage. Novel regenerative strategies are urgently awaited. Cultured …

In this study, we demonstrate that forkhead box F1 (FOXF1), a mesenchymal transcriptional
factor essential for lung development, was retained in a topographically distinct …

Dysregulation of the autotaxin (ATX, Enpp2)‐lysophosphatidic acid (LPA) signaling in
cancerous cells contributes to tumorigenesis and therapy resistance. We previously found …

Background Small airway inflammation and fibrosis or bronchiolitis obliterans (BO) is the
predominant presentation of chronic lung allograft dysfunction (CLAD) post-lung …

Acute respiratory distress syndrome/acute lung injury (ARDS/ALI) involves acute respiratory
failure characterized by vascular endothelial and lung alveolar epithelial injury. Endothelial …