Thoroughly updated with DSM-5 content throughout, Principles of Trauma Therapy, Second
Edition: DSM-5 Update is both comprehensive in scope and highly practical in application …

Epigenetic alterations offer promise as diagnostic or prognostic markers, but it is not known
whether these measures associate with, or predict, clinical state. These questions were …

As it has become clear that most individuals exposed to trauma do not develop PTSD, it has
become increasingly important to examine pretrauma risk factors. However, PTSD research …

Epidemiologic and genetic studies suggest common environmental and genetic risk factors
for a number of psychiatric disorders, including depression, bipolar disorder, and …

Neurobiological systems may be particularly susceptible to the deleterious impact of
childhood trauma, and the impact of childhood trauma on development and subsequent …

Extensive research has identified stereotypic behavioral and biological abnormalities in post-
traumatic stress disorder (PTSD), such as heightened autonomic activity, an exaggerated …

The high prevalence of trauma exposure and subsequent negative consequences for both
survivors and society as a whole emphasize the need for secondary prevention of …

Psychiatric phenotypes are multifactorial and polygenic, resulting from the complex interplay
of genes and environmental factors that act cumulatively throughout an organism's lifetime …

Background Gene-environment interaction contributes to the risks of psychiatric disorders.
Interactions between FKBP5 gene variants and early-life stress may enhance the risk not …

There is a growing body of research focused on the relationship between childhood trauma
and the risk of developing psychosis. Numerous studies, including many large-scale …