Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy
Hepatocellular carcinoma (HCC) mortality rates are increasing globally, and particularly in
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …
Friend or foe? The elusive role of hepatic stellate cells in liver cancer
B Cogliati, CN Yashaswini, S Wang, D Sia… - Nature Reviews …, 2023 - nature.com
Liver fibrosis is a substantial risk factor for the development and progression of liver cancer,
which includes hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma …
which includes hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma …
Nonalcoholic fatty liver disease and hepatocellular carcinoma: Insights in epidemiology, pathogenesis, imaging, prevention and therapy
SA Polyzos, L Chrysavgis, ID Vachliotis… - Seminars in cancer …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is estimated to be the third leading cause of cancer-related
mortality and is characterized by low survival rates. Nonalcoholic fatty liver disease (NAFLD) …
mortality and is characterized by low survival rates. Nonalcoholic fatty liver disease (NAFLD) …
[HTML][HTML] Invited review liver fibrosis in NAFLD/NASH: From pathophysiology towards diagnostic and therapeutic strategies
Liver fibrosis, as an excess deposition of extracellular matrix (ECM) components, results
from chronic liver injury as well as persistent activation of inflammatory response and of …
from chronic liver injury as well as persistent activation of inflammatory response and of …
Precision treatment in advanced hepatocellular carcinoma
X Yang, C Yang, S Zhang, H Geng, AX Zhu… - Cancer Cell, 2024 - cell.com
The past decade has witnessed significant advances in the systemic treatment of advanced
hepatocellular carcinoma (HCC). Nevertheless, the newly developed treatment strategies …
hepatocellular carcinoma (HCC). Nevertheless, the newly developed treatment strategies …
Adjuvant and neoadjuvant immunotherapies in hepatocellular carcinoma
Liver cancer, specifically hepatocellular carcinoma (HCC), is the sixth most common cancer
and the third leading cause of cancer mortality worldwide. The development of effective …
and the third leading cause of cancer mortality worldwide. The development of effective …
MAFLD: an optimal framework for understanding liver cancer phenotypes
H Crane, C Gofton, A Sharma, J George - Journal of Gastroenterology, 2023 - Springer
Hepatocellular carcinoma has a substantial global mortality burden which is rising despite
advancements in tackling the traditional viral risk factors. Metabolic (dysfunction) associated …
advancements in tackling the traditional viral risk factors. Metabolic (dysfunction) associated …
Human diet‐derived polyphenolic compounds and hepatic diseases: From therapeutic mechanisms to clinical utilization
Q Hu, W Zhang, F Wei, M Huang, M Shu… - Phytotherapy …, 2024 - Wiley Online Library
This review focuses on the potential ameliorative effects of polyphenolic compounds derived
from human diet on hepatic diseases. It discusses the molecular mechanisms and recent …
from human diet on hepatic diseases. It discusses the molecular mechanisms and recent …
Semaglutide reduces tumor burden in the GAN diet-induced obese and biopsy-confirmed mouse model of NASH-HCC with advanced fibrosis
HH Hansen, S Pors, MW Andersen, M Vyberg… - Scientific Reports, 2023 - nature.com
Non-alcoholic steatohepatitis (NASH) is emerging as a major cause of hepatocellular
carcinoma (HCC), however, it is not resolved if compounds in late-stage clinical …
carcinoma (HCC), however, it is not resolved if compounds in late-stage clinical …
Inflammation and digestive cancer
H Waldum, R Fossmark - International Journal of Molecular Sciences, 2023 - mdpi.com
Chronic inflammation is linked to carcinogenesis, particularly in the digestive organs, ie, the
stomach, colon, and liver. The mechanism of this effect has, however, only partly been …
stomach, colon, and liver. The mechanism of this effect has, however, only partly been …